Of flaky tails and itchy skin

Research output: Contribution to journalShort surveypeer-review

13 Scopus citations


A new study defines the flaky tail mouse as a model for human atopic dermatitis caused by a null mutation in the gene encoding filaggrin, a key component of the epidermal barrier. Research in these mice will help explain how a disrupted barrier contributes to the pathogenesis of atopic dermatitis and to asthma arising in the context of atopic skin disease.

Original languageEnglish (US)
Pages (from-to)512-513
Number of pages2
JournalNature Genetics
Issue number5
StatePublished - May 2009

ASJC Scopus subject areas

  • Genetics


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