Odoratin and paucin: Cytotoxic sesquiterpene lactones from, Baileya pauciradiata (compositae)

Joseph J. Hoffmann; Shivanand D. Jolad; Sterling J. Torrance; Dori J. Luzbetak; Richard M. Wiedhopf; Jack R. Cole

doi:10.1002/jps.2600671136

Odoratin and paucin: Cytotoxic sesquiterpene lactones from, Baileya pauciradiata (compositae)

Joseph J. Hoffmann
, Shivanand D. Jolad
, Sterling J. Torrance
, Dori J. Luzbetak
, Richard M. Wiedhopf
, Jack R. Cole

Research output: Contribution to journal › Comment/debate › peer-review

7 Scopus citations

Abstract

An ethanol extract of Baileya pauciradiata exhibited cytotoxic activity against the human epidermoid carcinoma of the nasopharynx and the lymphocytic leukemia test systems. Two constituents responsible for this activity were isolated and identified as odoratin and paucin. Their identities were proven by IR, PMR, and mass spectral data; elemental analysis; preparation of their acetates; and melting‐point determinations. Odoratin was confirmed by comparison with an authentic sample.

Original language	English (US)
Pages (from-to)	1633-1634
Number of pages	2
Journal	Journal of pharmaceutical sciences
Volume	67
Issue number	11
DOIs	https://doi.org/10.1002/jps.2600671136
State	Published - Nov 1978
Externally published	Yes

Keywords

Baileya pauciradiata—whole plant ethanol extract, odoratin and paucin isolated and identified
Cytotoxic sesquiterpene lactones—odoratin and paucin, isolated from whole plant ethanol extract of Baileya pauciradiata
Odoratin—isolated and identified from whole plant ethanol extract of Baileya pauciradiata
Paucin—isolated and identified from whole plant ethanol extract of Baileya pauciradiata

ASJC Scopus subject areas

Pharmaceutical Science

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10.1002/jps.2600671136

Cite this

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title = "Odoratin and paucin: Cytotoxic sesquiterpene lactones from, Baileya pauciradiata (compositae)",

abstract = "An ethanol extract of Baileya pauciradiata exhibited cytotoxic activity against the human epidermoid carcinoma of the nasopharynx and the lymphocytic leukemia test systems. Two constituents responsible for this activity were isolated and identified as odoratin and paucin. Their identities were proven by IR, PMR, and mass spectral data; elemental analysis; preparation of their acetates; and melting‐point determinations. Odoratin was confirmed by comparison with an authentic sample.",

keywords = "Baileya pauciradiata—whole plant ethanol extract, odoratin and paucin isolated and identified, Cytotoxic sesquiterpene lactones—odoratin and paucin, isolated from whole plant ethanol extract of Baileya pauciradiata, Odoratin—isolated and identified from whole plant ethanol extract of Baileya pauciradiata, Paucin—isolated and identified from whole plant ethanol extract of Baileya pauciradiata",

author = "Hoffmann, \{Joseph J.\} and Jolad, \{Shivanand D.\} and Torrance, \{Sterling J.\} and Luzbetak, \{Dori J.\} and Wiedhopf, \{Richard M.\} and Cole, \{Jack R.\}",

year = "1978",

month = nov,

doi = "10.1002/jps.2600671136",

language = "English (US)",

volume = "67",

pages = "1633--1634",

journal = "Journal of pharmaceutical sciences",

issn = "0022-3549",

publisher = "Elsevier B.V.",

number = "11",

}

TY - JOUR

T1 - Odoratin and paucin

T2 - Cytotoxic sesquiterpene lactones from, Baileya pauciradiata (compositae)

AU - Hoffmann, Joseph J.

AU - Jolad, Shivanand D.

AU - Torrance, Sterling J.

AU - Luzbetak, Dori J.

AU - Wiedhopf, Richard M.

AU - Cole, Jack R.

PY - 1978/11

Y1 - 1978/11

N2 - An ethanol extract of Baileya pauciradiata exhibited cytotoxic activity against the human epidermoid carcinoma of the nasopharynx and the lymphocytic leukemia test systems. Two constituents responsible for this activity were isolated and identified as odoratin and paucin. Their identities were proven by IR, PMR, and mass spectral data; elemental analysis; preparation of their acetates; and melting‐point determinations. Odoratin was confirmed by comparison with an authentic sample.

AB - An ethanol extract of Baileya pauciradiata exhibited cytotoxic activity against the human epidermoid carcinoma of the nasopharynx and the lymphocytic leukemia test systems. Two constituents responsible for this activity were isolated and identified as odoratin and paucin. Their identities were proven by IR, PMR, and mass spectral data; elemental analysis; preparation of their acetates; and melting‐point determinations. Odoratin was confirmed by comparison with an authentic sample.

KW - Baileya pauciradiata—whole plant ethanol extract, odoratin and paucin isolated and identified

KW - Cytotoxic sesquiterpene lactones—odoratin and paucin, isolated from whole plant ethanol extract of Baileya pauciradiata

KW - Odoratin—isolated and identified from whole plant ethanol extract of Baileya pauciradiata

KW - Paucin—isolated and identified from whole plant ethanol extract of Baileya pauciradiata

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UR - https://www.scopus.com/pages/publications/0018162357#tab=citedBy

U2 - 10.1002/jps.2600671136

DO - 10.1002/jps.2600671136

M3 - Comment/debate

C2 - 712609

AN - SCOPUS:0018162357

SN - 0022-3549

VL - 67

SP - 1633

EP - 1634

JO - Journal of pharmaceutical sciences

JF - Journal of pharmaceutical sciences

IS - 11

ER -

Odoratin and paucin: Cytotoxic sesquiterpene lactones from, Baileya pauciradiata (compositae)

Abstract

Keywords

ASJC Scopus subject areas

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