Obstructive airway disease as a risk factor for asbestos-associated malignancy

Philip Harber, Ami Oren, Zab Mohsenifar, Myron Lew

Research output: Contribution to journalArticlepeer-review

5 Scopus citations


A case-control study of a heavily asbestos-exposed group was performed to determine if obstructive airway disorder is an independent risk factor for developing asbestos-associated malignancies. From a group of 1,500 asbestos workers who had previously undergone careful evaluation, 18 case employees were identified. Each case employee was matched by smoking status, pack-years, age, and years of asbestos exposure to a single referent, a member of the same exposed population known to be free of malignancy. The spirometry results, obtained prior to the clinical manifestation of the cancer, were compared. The FEVl/FVC ratio and the FEV1/ heightf ratio were lower (P < .05, P < .10, respectively) in the case employees. These results suggest that obstructive airway disease may be an independent risk factor for cancer.

Original languageEnglish (US)
Pages (from-to)82-86
Number of pages5
JournalJournal of Occupational Medicine
Issue number2
StatePublished - Feb 1986
Externally publishedYes

ASJC Scopus subject areas

  • Public Health, Environmental and Occupational Health


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