A case-control study of a heavily asbestos-exposed group was performed to determine if obstructive airway disorder is an independent risk factor for developing asbestos-associated malignancies. From a group of 1,500 asbestos workers who had previously undergone careful evaluation, 18 case employees were identified. Each case employee was matched by smoking status, pack-years, age, and years of asbestos exposure to a single referent, a member of the same exposed population known to be free of malignancy. The spirometry results, obtained prior to the clinical manifestation of the cancer, were compared. The FEVl/FVC ratio and the FEV1/ heightf ratio were lower (P < .05, P < .10, respectively) in the case employees. These results suggest that obstructive airway disease may be an independent risk factor for cancer.
|Original language||English (US)|
|Number of pages||5|
|Journal||Journal of Occupational Medicine|
|State||Published - Feb 1986|
ASJC Scopus subject areas
- Public Health, Environmental and Occupational Health