Abstract
In solid-phase peptide synthesis, it is desirable to incorporate both serine and threonine as their O-ben-zyl-N-acyloxycarbonyl derivatives.8 Recently, a simple method for preparing O-benzyl-N-if-butyloxycarbonyl-L-threonine was reported.4 On the other hand, methods for preparing O-benzyl-N-i-butyloxycarbonyl-L-serine are very laborious.6-6 The present study reports a simple two-step synthesis of O-benzyl-N-i-butyloxycarbonyl-L-serine from L-serine.
Original language | English (US) |
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Pages (from-to) | 1690 |
Number of pages | 1 |
Journal | Journal of Organic Chemistry |
Volume | 35 |
Issue number | 5 |
DOIs |
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State | Published - May 1 1970 |
Externally published | Yes |
ASJC Scopus subject areas
- Organic Chemistry