Novel use of insulin in continuous-instillation negative pressure wound therapy as "wound chemotherapy"

Christy L. Scimeca; Manish Bharara; Timothy K. Fisher; Heather Kimbriel; Joseph L. Mills; David G. Armstrong

doi:10.1177/193229681000400408

Novel use of insulin in continuous-instillation negative pressure wound therapy as "wound chemotherapy"

Christy L. Scimeca, Manish Bharara, Timothy K. Fisher, Heather Kimbriel, Joseph L. Mills, David G. Armstrong

Surgery

Research output: Contribution to journal › Article › peer-review

26 Scopus citations

Abstract

Negative pressure wound therapy (NPWT) is frequently employed in the treatment of complex wounds. A variety of wound chemotherapeutic agents such as insulin, which acts as a growth factor, may prove helpful in treatment as well. We present a case report in which insulin was used as a chemotherapeutic agent in continuous-instillation NPWT. To our knowledge, this is the first report in the literature describing this method of delivery.

Original language	English (US)
Pages (from-to)	820-824
Number of pages	5
Journal	Journal of Diabetes Science and Technology
Volume	4
Issue number	4
DOIs	https://doi.org/10.1177/193229681000400408
State	Published - Jul 2010

Keywords

Diabetic foot ulcers
Insulin
Negative pressure wound therapy
Wound chemotherapy

ASJC Scopus subject areas

Internal Medicine
Endocrinology, Diabetes and Metabolism
Bioengineering
Biomedical Engineering

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10.1177/193229681000400408

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abstract = "Negative pressure wound therapy (NPWT) is frequently employed in the treatment of complex wounds. A variety of wound chemotherapeutic agents such as insulin, which acts as a growth factor, may prove helpful in treatment as well. We present a case report in which insulin was used as a chemotherapeutic agent in continuous-instillation NPWT. To our knowledge, this is the first report in the literature describing this method of delivery.",

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AU - Scimeca, Christy L.

AU - Bharara, Manish

AU - Fisher, Timothy K.

AU - Kimbriel, Heather

AU - Mills, Joseph L.

AU - Armstrong, David G.

PY - 2010/7

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N2 - Negative pressure wound therapy (NPWT) is frequently employed in the treatment of complex wounds. A variety of wound chemotherapeutic agents such as insulin, which acts as a growth factor, may prove helpful in treatment as well. We present a case report in which insulin was used as a chemotherapeutic agent in continuous-instillation NPWT. To our knowledge, this is the first report in the literature describing this method of delivery.

AB - Negative pressure wound therapy (NPWT) is frequently employed in the treatment of complex wounds. A variety of wound chemotherapeutic agents such as insulin, which acts as a growth factor, may prove helpful in treatment as well. We present a case report in which insulin was used as a chemotherapeutic agent in continuous-instillation NPWT. To our knowledge, this is the first report in the literature describing this method of delivery.

KW - Diabetic foot ulcers

KW - Insulin

KW - Negative pressure wound therapy

KW - Wound chemotherapy

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Novel use of insulin in continuous-instillation negative pressure wound therapy as "wound chemotherapy"

Abstract

Keywords

ASJC Scopus subject areas

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