Novel superparamagnetic core(shell) nanoparticles for magnetic targeted drug delivery and hyperthermia treatment

Palash Gangopadhyay; Sébastien Gallet; Edith Franz; André Persoons; Thierry Verbiest

doi:10.1109/TMAG.2005.854805

Novel superparamagnetic core(shell) nanoparticles for magnetic targeted drug delivery and hyperthermia treatment

Palash Gangopadhyay, Sébastien Gallet, Edith Franz, André Persoons, Thierry Verbiest

Optical Sciences, College of

Research output: Contribution to journal › Article › peer-review

70 Scopus citations

Abstract

Superparamagnetic γ-Fe₂O₃ (Au) core(shell) nanoparticles with narrow size distribution and different shell thicknesses are synthesized. On conjugation with serum albumin, this set of particles forms an ideal candidate to be used in magnetic targeted drug delivery and hyperthermia treatment. In this contribution, the synthesis and characterizations of their size, optical, and magnetic properties are reported. It has also been shown that using different shell thicknesses, it is possible to tune not only the plasmon response of the gold shell but also the magnetic property of these Superparamagnetic nanoparticles.

Original language	English (US)
Pages (from-to)	4194-4196
Number of pages	3
Journal	IEEE Transactions on Magnetics
Volume	41
Issue number	10
DOIs	https://doi.org/10.1109/TMAG.2005.854805
State	Published - Oct 2005

Keywords

Core(shell) nanoparticles
Hyperthermia, maghemite (gold)
Magnetic targeted drug delivery

ASJC Scopus subject areas

Electronic, Optical and Magnetic Materials
Electrical and Electronic Engineering

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10.1109/TMAG.2005.854805

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title = "Novel superparamagnetic core(shell) nanoparticles for magnetic targeted drug delivery and hyperthermia treatment",

abstract = "Superparamagnetic γ-Fe2O3 (Au) core(shell) nanoparticles with narrow size distribution and different shell thicknesses are synthesized. On conjugation with serum albumin, this set of particles forms an ideal candidate to be used in magnetic targeted drug delivery and hyperthermia treatment. In this contribution, the synthesis and characterizations of their size, optical, and magnetic properties are reported. It has also been shown that using different shell thicknesses, it is possible to tune not only the plasmon response of the gold shell but also the magnetic property of these Superparamagnetic nanoparticles.",

keywords = "Core(shell) nanoparticles, Hyperthermia, maghemite (gold), Magnetic targeted drug delivery",

author = "Palash Gangopadhyay and S{\'e}bastien Gallet and Edith Franz and Andr{\'e} Persoons and Thierry Verbiest",

note = "Funding Information: This work was supported by Fund for Scientific Research-Flanders (FWO-Vlaanderen; G.0260.03, G.0297.04), the Katholieke Universiteit Leuven (GOA/2000/03), and the Belgian Government (IUAP P5/03). The authors thank W. Vinckx, V. Moshalkov, and R. de Vos for their help with SQUID and SEM measurements.",

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doi = "10.1109/TMAG.2005.854805",

language = "English (US)",

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journal = "IEEE Transactions on Magnetics",

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AU - Gangopadhyay, Palash

AU - Gallet, Sébastien

AU - Franz, Edith

AU - Persoons, André

AU - Verbiest, Thierry

N1 - Funding Information: This work was supported by Fund for Scientific Research-Flanders (FWO-Vlaanderen; G.0260.03, G.0297.04), the Katholieke Universiteit Leuven (GOA/2000/03), and the Belgian Government (IUAP P5/03). The authors thank W. Vinckx, V. Moshalkov, and R. de Vos for their help with SQUID and SEM measurements.

PY - 2005/10

Y1 - 2005/10

N2 - Superparamagnetic γ-Fe2O3 (Au) core(shell) nanoparticles with narrow size distribution and different shell thicknesses are synthesized. On conjugation with serum albumin, this set of particles forms an ideal candidate to be used in magnetic targeted drug delivery and hyperthermia treatment. In this contribution, the synthesis and characterizations of their size, optical, and magnetic properties are reported. It has also been shown that using different shell thicknesses, it is possible to tune not only the plasmon response of the gold shell but also the magnetic property of these Superparamagnetic nanoparticles.

AB - Superparamagnetic γ-Fe2O3 (Au) core(shell) nanoparticles with narrow size distribution and different shell thicknesses are synthesized. On conjugation with serum albumin, this set of particles forms an ideal candidate to be used in magnetic targeted drug delivery and hyperthermia treatment. In this contribution, the synthesis and characterizations of their size, optical, and magnetic properties are reported. It has also been shown that using different shell thicknesses, it is possible to tune not only the plasmon response of the gold shell but also the magnetic property of these Superparamagnetic nanoparticles.

KW - Core(shell) nanoparticles

KW - Hyperthermia, maghemite (gold)

KW - Magnetic targeted drug delivery

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Novel superparamagnetic core(shell) nanoparticles for magnetic targeted drug delivery and hyperthermia treatment

Abstract

Keywords

ASJC Scopus subject areas

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