Nonopioid Actions of Intrathecal Dynorphin Evoke Spinal Excitatory Amino Acid and Prostaglandin E₂ Release Mediated by Cyclooxygenase-1 and -2

Keyphrases

• Prostaglandin E2 100%
• Dynorphin 100%
• Excitatory Amino Acids 100%
• Intrathecal 100%
• Non-opioid 100%
• Cyclooxygenase-1/2 100%
• Dynorphin A 80%
• Prostaglandins 40%
• Hyperalgesia 40%
• Cyclooxygenase-1 (COX-1) 40%
• Novel Mechanism 20%
• Nerve Injury 20%
• Intrathecal Injection 20%
• Dialysis 20%
• Lumbar 20%
• Glutamate 20%
• Tissue Injury 20%
• Isozymes 20%
• Morphine Exposure 20%
• Pathological Conditions 20%
• Amino 20%
• Cyclooxygenase Inhibitors 20%
• Aspartate 20%
• Cyclooxygenase-2 Inhibitors 20%
• Unanesthetized 20%
• NMDA Antagonist 20%

Pharmacology, Toxicology and Pharmaceutical Science

• Intrathecal 100%
• Dynorphin 100%
• Prostaglandin E2 100%
• Excitatory Amino Acid 100%
• Cyclooxygenase 1 100%
• N Methyl Dextro Aspartic Acid 80%
• Dynorphin A 80%
• Hyperalgesia 40%
• Prostaglandin 40%
• Morphine 20%
• Tissue Injury 20%
• Nerve Injury 20%
• Aspartic Acid 20%
• COX-2 Inhibitor 20%
• Serine 20%
• Glutamic Acid 20%
• Isoenzyme 20%
• Prostaglandin Synthase 20%
• Prostaglandin Synthase Inhibitor 20%
• N Methyl Dextro Aspartic Acid Receptor Blocking Agent 20%
• Ibuprofen 20%
• Cyclooxygenase 1 Inhibitor 20%

Neuroscience

• Intrathecal 100%
• Prostaglandin E2 100%
• Excitatory Amino Acid 100%
• Dynorphin 100%
• Cyclooxygenase 1 100%
• N-Methyl-D-Aspartic Acid 80%
• Dynorphin A 80%
• Hyperalgesia 40%
• Prostaglandin 40%
• Cyclooxygenase 40%
• NMDA Receptor Antagonist 20%
• Morphine 20%
• Glutamic Acid 20%
• Aspartic Acid 20%
• Serine 20%
• Isoenzyme 20%
• COX-2 Inhibitor 20%
• Ibuprofen 20%