Non-invasive transabdominal measurement of placental oxygenation: A step toward continuous monitoring

Thien Nguyen; Kosar Khaksari; Siddharth M. Khare; Soongho Park; Afrouz A. Anderson; Janine Bieda; Eunjung Jung; Chaur Dong Hsu; Roberto Romero; Amir H. Gandjbakhche

doi:10.1364/BOE.424969

Non-invasive transabdominal measurement of placental oxygenation: A step toward continuous monitoring

Thien Nguyen, Kosar Khaksari, Siddharth M. Khare, Soongho Park, Afrouz A. Anderson, Janine Bieda, Eunjung Jung, Chaur Dong Hsu, Roberto Romero, Amir H. Gandjbakhche

Research output: Contribution to journal › Article › peer-review

Abstract

This study aimed to assess transabdominal placental oxygenation levels non-invasively. A wearable device was designed and tested in 12 pregnant women with an anterior placenta, 5 of whom had maternal pregnancy complications. Preliminary results revealed that the placental oxygenation level is closely related to pregnancy complications and placental pathology. Women with maternal pregnancy complications were found to have a lower placental oxygenation level (69.4% ± 6.7%) than those with uncomplicated pregnancy (75.0% ± 5.8%). This device is a step in the development of a point-of-care method designed to continuously monitor placental oxygenation and to assess maternal and fetal health.

Original language	English (US)
Pages (from-to)	4119-4130
Number of pages	12
Journal	Biomedical Optics Express
Volume	12
Issue number	7
DOIs	https://doi.org/10.1364/BOE.424969
State	Published - Jul 1 2021
Externally published	Yes

ASJC Scopus subject areas

Biotechnology
Atomic and Molecular Physics, and Optics

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10.1364/BOE.424969

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Non-invasive transabdominal measurement of placental oxygenation : A step toward continuous monitoring. / Nguyen, Thien; Khaksari, Kosar; Khare, Siddharth M.; Park, Soongho; Anderson, Afrouz A.; Bieda, Janine; Jung, Eunjung; Hsu, Chaur Dong; Romero, Roberto; Gandjbakhche, Amir H.

In: Biomedical Optics Express, Vol. 12, No. 7, 01.07.2021, p. 4119-4130.

Research output: Contribution to journal › Article › peer-review

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abstract = "This study aimed to assess transabdominal placental oxygenation levels non-invasively. A wearable device was designed and tested in 12 pregnant women with an anterior placenta, 5 of whom had maternal pregnancy complications. Preliminary results revealed that the placental oxygenation level is closely related to pregnancy complications and placental pathology. Women with maternal pregnancy complications were found to have a lower placental oxygenation level (69.4% ± 6.7%) than those with uncomplicated pregnancy (75.0% ± 5.8%). This device is a step in the development of a point-of-care method designed to continuously monitor placental oxygenation and to assess maternal and fetal health.",

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AU - Anderson, Afrouz A.

AU - Bieda, Janine

AU - Jung, Eunjung

AU - Hsu, Chaur Dong

AU - Romero, Roberto

AU - Gandjbakhche, Amir H.

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AB - This study aimed to assess transabdominal placental oxygenation levels non-invasively. A wearable device was designed and tested in 12 pregnant women with an anterior placenta, 5 of whom had maternal pregnancy complications. Preliminary results revealed that the placental oxygenation level is closely related to pregnancy complications and placental pathology. Women with maternal pregnancy complications were found to have a lower placental oxygenation level (69.4% ± 6.7%) than those with uncomplicated pregnancy (75.0% ± 5.8%). This device is a step in the development of a point-of-care method designed to continuously monitor placental oxygenation and to assess maternal and fetal health.

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Non-invasive transabdominal measurement of placental oxygenation: A step toward continuous monitoring

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