Non-invasive transabdominal measurement of placental oxygenation: A step toward continuous monitoring

Thien Nguyen, Kosar Khaksari, Siddharth M. Khare, Soongho Park, Afrouz A. Anderson, Janine Bieda, Eunjung Jung, Chaur Dong Hsu, Roberto Romero, Amir H. Gandjbakhche

Research output: Contribution to journalArticlepeer-review

Abstract

This study aimed to assess transabdominal placental oxygenation levels non-invasively. A wearable device was designed and tested in 12 pregnant women with an anterior placenta, 5 of whom had maternal pregnancy complications. Preliminary results revealed that the placental oxygenation level is closely related to pregnancy complications and placental pathology. Women with maternal pregnancy complications were found to have a lower placental oxygenation level (69.4% ± 6.7%) than those with uncomplicated pregnancy (75.0% ± 5.8%). This device is a step in the development of a point-of-care method designed to continuously monitor placental oxygenation and to assess maternal and fetal health.

Original languageEnglish (US)
Pages (from-to)4119-4130
Number of pages12
JournalBiomedical Optics Express
Volume12
Issue number7
DOIs
StatePublished - Jul 1 2021
Externally publishedYes

ASJC Scopus subject areas

  • Biotechnology
  • Atomic and Molecular Physics, and Optics

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