Non-enzymatic glucose detection based on phenylboronic acid modified optical fibers

Xiaolan Sun; Nana Li; Bin Zhou; Wei Zhao; Liyuan Liu; Chao Huang; Longfei Ma; Alan R. Kost

doi:10.1016/j.optcom.2018.01.064

Non-enzymatic glucose detection based on phenylboronic acid modified optical fibers

Xiaolan Sun, Nana Li, Bin Zhou, Wei Zhao, Liyuan Liu, Chao Huang, Longfei Ma, Alan R. Kost

Optical Sciences

Research output: Contribution to journal › Article › peer-review

26 Scopus citations

Abstract

A non-enzymatic, sensitive glucose sensor was fabricated based on an evanescent wave absorbing optical fiber probe. The optical fiber sensor was functionalized by fixing a poly (phenylboronic acid) (polyPBA) film onto the conical region of the single mode fiber. The reflected light intensity of the polyPBA-functionalized fiber sensor increased proportionally with glucose concentration in the range of 0–60 mM, and the sensor showed good reproducibility and stability. The developed sensor possessed a high sensitivity of 0.1787%/mM and good linearity. The measurement of glucose concentration in human serum was also demonstrated.

Original language	English (US)
Pages (from-to)	32-35
Number of pages	4
Journal	Optics Communications
Volume	416
DOIs	https://doi.org/10.1016/j.optcom.2018.01.064
State	Published - Jun 1 2018

Keywords

Evanescent wave
Glucose sensor
Phenylboronic acid (PBA)
Tapered optical fiber

ASJC Scopus subject areas

Electronic, Optical and Magnetic Materials
Atomic and Molecular Physics, and Optics
Physical and Theoretical Chemistry
Electrical and Electronic Engineering

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10.1016/j.optcom.2018.01.064

Cite this

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title = "Non-enzymatic glucose detection based on phenylboronic acid modified optical fibers",

abstract = "A non-enzymatic, sensitive glucose sensor was fabricated based on an evanescent wave absorbing optical fiber probe. The optical fiber sensor was functionalized by fixing a poly (phenylboronic acid) (polyPBA) film onto the conical region of the single mode fiber. The reflected light intensity of the polyPBA-functionalized fiber sensor increased proportionally with glucose concentration in the range of 0–60 mM, and the sensor showed good reproducibility and stability. The developed sensor possessed a high sensitivity of 0.1787%/mM and good linearity. The measurement of glucose concentration in human serum was also demonstrated.",

keywords = "Evanescent wave, Glucose sensor, Phenylboronic acid (PBA), Tapered optical fiber",

author = "Xiaolan Sun and Nana Li and Bin Zhou and Wei Zhao and Liyuan Liu and Chao Huang and Longfei Ma and Kost, {Alan R.}",

note = "Funding Information: This work was funded by the National Natural Science Foundation of China ( 61377040 ). Publisher Copyright: {\textcopyright} 2018 Elsevier B.V.",

year = "2018",

month = jun,

day = "1",

doi = "10.1016/j.optcom.2018.01.064",

language = "English (US)",

volume = "416",

pages = "32--35",

journal = "Optics Communications",

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TY - JOUR

T1 - Non-enzymatic glucose detection based on phenylboronic acid modified optical fibers

AU - Sun, Xiaolan

AU - Li, Nana

AU - Zhou, Bin

AU - Zhao, Wei

AU - Liu, Liyuan

AU - Huang, Chao

AU - Ma, Longfei

AU - Kost, Alan R.

PY - 2018/6/1

Y1 - 2018/6/1

N2 - A non-enzymatic, sensitive glucose sensor was fabricated based on an evanescent wave absorbing optical fiber probe. The optical fiber sensor was functionalized by fixing a poly (phenylboronic acid) (polyPBA) film onto the conical region of the single mode fiber. The reflected light intensity of the polyPBA-functionalized fiber sensor increased proportionally with glucose concentration in the range of 0–60 mM, and the sensor showed good reproducibility and stability. The developed sensor possessed a high sensitivity of 0.1787%/mM and good linearity. The measurement of glucose concentration in human serum was also demonstrated.

AB - A non-enzymatic, sensitive glucose sensor was fabricated based on an evanescent wave absorbing optical fiber probe. The optical fiber sensor was functionalized by fixing a poly (phenylboronic acid) (polyPBA) film onto the conical region of the single mode fiber. The reflected light intensity of the polyPBA-functionalized fiber sensor increased proportionally with glucose concentration in the range of 0–60 mM, and the sensor showed good reproducibility and stability. The developed sensor possessed a high sensitivity of 0.1787%/mM and good linearity. The measurement of glucose concentration in human serum was also demonstrated.

KW - Evanescent wave

KW - Glucose sensor

KW - Phenylboronic acid (PBA)

KW - Tapered optical fiber

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SN - 0030-4018

VL - 416

SP - 32

EP - 35

JO - Optics Communications

JF - Optics Communications

ER -

Non-enzymatic glucose detection based on phenylboronic acid modified optical fibers

Abstract

Keywords

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