TY - JOUR
T1 - NMR elastometry of fluid membranes in the mesoscopic regime
AU - Martinez, Gary V.
AU - Dykstra, Emily M.
AU - Lope-Piedrafita, Silvia
AU - Job, Constantin
AU - Brown, Michael F.
PY - 2002/11/27
Y1 - 2002/11/27
N2 - In solid-state [formula presented] NMR of fluid lipid bilayers, quasielastic deformations at MHz frequencies are detected as a square-law dependence of the nuclear spin-lattice [formula presented] relaxation rates and order parameters [formula presented] The signature square-law slope is found to decrease progressively with the mole fraction of cholesterol and with the acyl chain length, due to a stiffening of the membrane. The correspondence to thermal vesicle fluctuations and molecular dynamics simulations implies that a broad distribution of modes is present, ranging from the membrane size down to the molecular dimensions.
AB - In solid-state [formula presented] NMR of fluid lipid bilayers, quasielastic deformations at MHz frequencies are detected as a square-law dependence of the nuclear spin-lattice [formula presented] relaxation rates and order parameters [formula presented] The signature square-law slope is found to decrease progressively with the mole fraction of cholesterol and with the acyl chain length, due to a stiffening of the membrane. The correspondence to thermal vesicle fluctuations and molecular dynamics simulations implies that a broad distribution of modes is present, ranging from the membrane size down to the molecular dimensions.
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U2 - 10.1103/PhysRevE.66.050902
DO - 10.1103/PhysRevE.66.050902
M3 - Article
C2 - 12513460
AN - SCOPUS:85036140697
SN - 1063-651X
VL - 66
SP - 4
JO - Physical Review E - Statistical Physics, Plasmas, Fluids, and Related Interdisciplinary Topics
JF - Physical Review E - Statistical Physics, Plasmas, Fluids, and Related Interdisciplinary Topics
IS - 5
ER -