Nerve fiber conduction-velocity distributions. II. Estimation based on two compound action potentials

Kenneth L. Cummins, Leslie J. Dorfman, Donald H. Perkel

Research output: Contribution to journalArticlepeer-review

78 Scopus citations

Abstract

A method is presented for estimating nerve fiber conduction velocity distributions from non-ivasive measurements of the compound action potential at two distinct locations separated by a known distance along the nerve bundle. This method is based on a model of the compound action potential as a weighted sum of delayed single-fiber action potential, but does not require explicit knowlege of the single-fiber action potential wave shapes in order to yield a unique estimate of the conduction velocity distribution. Illustrative examples are presented from normal and diseased nerves. This method appears to have clinical applications in the electrophysiological assessment of peripheral nerve function.

Original languageEnglish (US)
Pages (from-to)647-658
Number of pages12
JournalElectroencephalography and Clinical Neurophysiology
Volume46
Issue number6
DOIs
StatePublished - Jun 1979
Externally publishedYes

ASJC Scopus subject areas

  • Neuroscience(all)
  • Clinical Neurology

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