Nerve fiber conduction-velocity distributions. I. Estimation based on the single-fiber and compound action potentials

Kenneth L. Cummins, Donald H. Perkel, Leslie J. Dorfman

Research output: Contribution to journalArticlepeer-review

96 Scopus citations

Abstract

A method is described for estimating the distribution of nerve-fiber conduction velocities in a nerve bundle. This method is based on a detailed general model of the nerve bundle compound action potential, which is characterized as a weighted sum of delayed single-fiber action potentials. The non-iterative estimation method is applied to two examples taken from existing literature, demonstrating the similarity of conduction velocity and fiber diameter distributions, sensitivity of the estimate to variations in important model parameters, and applicability to the differentiation of normal and abnormal nerve function.

Original languageEnglish (US)
Pages (from-to)634-646
Number of pages13
JournalElectroencephalography and Clinical Neurophysiology
Volume46
Issue number6
DOIs
StatePublished - Jun 1979
Externally publishedYes

ASJC Scopus subject areas

  • Neuroscience(all)
  • Clinical Neurology

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