Nanocrystals for the parenteral delivery of poorly water-soluble drugs

Bo Sun, Yoon Yeo

Research output: Contribution to journalReview articlepeer-review

92 Scopus citations

Abstract

Nanocrystals have drawn increasing interest in pharmaceutical industry because of the ability to improve dissolution of poorly water-soluble drugs. Nanocrystals can be produced by top-down and bottom-up technologies and have been explored for a variety of therapeutic applications. Here we review the methods of nanocrystal production and parenteral applications of nanocrystals. We also discuss remaining challenges in the development of nanocrystal products.

Original languageEnglish (US)
Pages (from-to)295-301
Number of pages7
JournalCurrent Opinion in Solid State and Materials Science
Volume16
Issue number6
DOIs
StatePublished - Dec 2012
Externally publishedYes

Keywords

  • Nanocrystals
  • Nanosuspension
  • Parenteral applications
  • Poorly water-soluble drugs

ASJC Scopus subject areas

  • Materials Science(all)

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