Nanobubble-enhanced sonothrombolysis: From benchtop to bedside

Evan C. Unger

Research output: Chapter in Book/Report/Conference proceedingConference contribution

1 Scopus citations


Microbubbles have been shown to enhance the rate of clot dissolution with ultrasound. In vivo work in a canine model has shown good efficacy for clot dissolution with ultrasound and intravenously administered MRX-815 nanobubbles (1,2). In this abstract we describe results in an in vitro clot lysis model with and without lytic drugs and also describe early results of clinical trials.

Original languageEnglish (US)
Title of host publicationTHERAPEUTIC ULTRASOUND
Subtitle of host publication5th International Symposium on Therapeutic Ultrasound
Number of pages3
StatePublished - May 8 2006
EventTHERAPEUTIC ULTRASOUND: 5th International Symposium on Therapeutic Ultrasound - Boston, MA, United States
Duration: Oct 27 2005Oct 29 2005

Publication series

NameAIP Conference Proceedings
ISSN (Print)0094-243X
ISSN (Electronic)1551-7616


OtherTHERAPEUTIC ULTRASOUND: 5th International Symposium on Therapeutic Ultrasound
Country/TerritoryUnited States
CityBoston, MA


  • Nanobubbles
  • Stroke
  • Thrombolysis

ASJC Scopus subject areas

  • General Physics and Astronomy


Dive into the research topics of 'Nanobubble-enhanced sonothrombolysis: From benchtop to bedside'. Together they form a unique fingerprint.

Cite this