Myelodysplastic transformation of polycythemia vera: Case report and review of the literature

Glenn J. Shamdas; Catherine M. Spier; Alan F. List

doi:10.1002/ajh.2830370110

Myelodysplastic transformation of polycythemia vera: Case report and review of the literature

Glenn J. Shamdas, Catherine M. Spier, Alan F. List

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14 Scopus citations

Abstract

We report a case of refractory anemia with excess blasts (RAEB) developing in a 67‐year old man with a history of polycythemia vera; results of cytogenetic and immunophenotyping studies are described. In this report the clinical, cytogenetic and hematologic features of myelodysplasia complicating polycythemia vera are reviewed. Results of immunophenotyping and cytogenetic studies, and the preponderance of cases developing after myelosuppressive therapy suggest that in the majority of cases myelodysplasia is treatment‐related.

Original language	English (US)
Pages (from-to)	45-48
Number of pages	4
Journal	American Journal of Hematology
Volume	37
Issue number	1
DOIs	https://doi.org/10.1002/ajh.2830370110
State	Published - May 1991

Keywords

cytogenic studies
immunophenotyping studies
myelodysplastic syndrome
polycythemia vera

ASJC Scopus subject areas

Hematology

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10.1002/ajh.2830370110

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abstract = "We report a case of refractory anemia with excess blasts (RAEB) developing in a 67‐year old man with a history of polycythemia vera; results of cytogenetic and immunophenotyping studies are described. In this report the clinical, cytogenetic and hematologic features of myelodysplasia complicating polycythemia vera are reviewed. Results of immunophenotyping and cytogenetic studies, and the preponderance of cases developing after myelosuppressive therapy suggest that in the majority of cases myelodysplasia is treatment‐related.",

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AB - We report a case of refractory anemia with excess blasts (RAEB) developing in a 67‐year old man with a history of polycythemia vera; results of cytogenetic and immunophenotyping studies are described. In this report the clinical, cytogenetic and hematologic features of myelodysplasia complicating polycythemia vera are reviewed. Results of immunophenotyping and cytogenetic studies, and the preponderance of cases developing after myelosuppressive therapy suggest that in the majority of cases myelodysplasia is treatment‐related.

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KW - immunophenotyping studies

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KW - polycythemia vera

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Myelodysplastic transformation of polycythemia vera: Case report and review of the literature

Abstract

Keywords

ASJC Scopus subject areas

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