Mutations leading to loss of sporulation ability in Bacillus subtilis are sufficiently frequent to favor genetic canalization

Joanna Masel, Heather Maughan

Research output: Contribution to journalArticlepeer-review

17 Scopus citations

Abstract

We measured the rate of mutations impairing sporulation ability in Bacillus subtilis as 0.003 in a mutator population, following 6000 generations of strong selection for sporulation that have previously been described. This means that the product of the population size and the functional mutation rate is ∼105, well within the parameter range for which genetic canalization of sporulation ability is expected.

Original languageEnglish (US)
Pages (from-to)453-457
Number of pages5
JournalGenetics
Volume175
Issue number1
DOIs
StatePublished - Jan 2007

ASJC Scopus subject areas

  • Genetics

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