TY - JOUR
T1 - Multipotent Mesenchymal Stromal Cells for Pulmonary Fibrosis?
AU - Purdon, Stefanie
AU - Patete, Carissa L.
AU - Glassberg, Marilyn K.
N1 - Publisher Copyright:
© 2019
PY - 2019/5
Y1 - 2019/5
N2 - With the combination of ideologic beliefs and the will to survive, fraught patients and determined clinicians seek alternative therapies for treatment of terminal conditions, such as idiopathic pulmonary fibrosis. Unfortunately, the need for treatment has supported the growth of unapproved stem cell therapy over the years spanning across many countries. The reality, however, is that the science behind this therapy is lagging. While there have been promising results from phase I trials, there remain multiple reasons that “stem cells” are not ready for clinical application, starting from a gap in understanding at the bench research level, all the way to optimal clinical application in order to provide effective therapy.
AB - With the combination of ideologic beliefs and the will to survive, fraught patients and determined clinicians seek alternative therapies for treatment of terminal conditions, such as idiopathic pulmonary fibrosis. Unfortunately, the need for treatment has supported the growth of unapproved stem cell therapy over the years spanning across many countries. The reality, however, is that the science behind this therapy is lagging. While there have been promising results from phase I trials, there remain multiple reasons that “stem cells” are not ready for clinical application, starting from a gap in understanding at the bench research level, all the way to optimal clinical application in order to provide effective therapy.
KW - Idiopathic pulmonary fibrosis
KW - Stem cells
KW - Therapies
UR - http://www.scopus.com/inward/record.url?scp=85063873972&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85063873972&partnerID=8YFLogxK
U2 - 10.1016/j.amjms.2019.02.007
DO - 10.1016/j.amjms.2019.02.007
M3 - Review article
C2 - 31010466
AN - SCOPUS:85063873972
SN - 0002-9629
VL - 357
SP - 390
EP - 393
JO - American Journal of the Medical Sciences
JF - American Journal of the Medical Sciences
IS - 5
ER -