Multiple Cholesterol Emboli Syndrome: Bowel Infarction After Retrograde Angiography

Robert C. Hendel, Henri F. Cuenoud, David F. Giansiracusa, Joseph S. Alpert

Research output: Contribution to journalArticlepeer-review

33 Scopus citations


The two patients described In this article are among the first to have been diagnosed with extensive bowel infarction as a result of cholesterol embolization following cardiac catheterization. The presence of acute hypertension, renal insufficiency, livedo reticularis, and gangrenous skin changes are characteristic manifestations of the multiple cholesterol emboli syndrome. Additionally, gastrointestinal symptoms and melena may herald ischemia and Infarction of the alimentary tract. Anticoagulation and thrombolytic therapy are relatively contraindicated In this syndrome and may, In fact, be a precipitating cause. The prognosis is usually poor; however, survival is possible with aggressive medical and surgical therapy, despite extensive infarction of the gastrointestinal tract and other organs. Prevention remains the most critical aspect of management of this potentially catastrophic illness.

Original languageEnglish (US)
Pages (from-to)2371-2374
Number of pages4
JournalArchives of internal medicine
Issue number10
StatePublished - Oct 1989

ASJC Scopus subject areas

  • Internal Medicine


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