TY - JOUR
T1 - Multiple Cholesterol Emboli Syndrome
T2 - Bowel Infarction After Retrograde Angiography
AU - Hendel, Robert C.
AU - Cuenoud, Henri F.
AU - Giansiracusa, David F.
AU - Alpert, Joseph S.
PY - 1989/10
Y1 - 1989/10
N2 - The two patients described In this article are among the first to have been diagnosed with extensive bowel infarction as a result of cholesterol embolization following cardiac catheterization. The presence of acute hypertension, renal insufficiency, livedo reticularis, and gangrenous skin changes are characteristic manifestations of the multiple cholesterol emboli syndrome. Additionally, gastrointestinal symptoms and melena may herald ischemia and Infarction of the alimentary tract. Anticoagulation and thrombolytic therapy are relatively contraindicated In this syndrome and may, In fact, be a precipitating cause. The prognosis is usually poor; however, survival is possible with aggressive medical and surgical therapy, despite extensive infarction of the gastrointestinal tract and other organs. Prevention remains the most critical aspect of management of this potentially catastrophic illness.
AB - The two patients described In this article are among the first to have been diagnosed with extensive bowel infarction as a result of cholesterol embolization following cardiac catheterization. The presence of acute hypertension, renal insufficiency, livedo reticularis, and gangrenous skin changes are characteristic manifestations of the multiple cholesterol emboli syndrome. Additionally, gastrointestinal symptoms and melena may herald ischemia and Infarction of the alimentary tract. Anticoagulation and thrombolytic therapy are relatively contraindicated In this syndrome and may, In fact, be a precipitating cause. The prognosis is usually poor; however, survival is possible with aggressive medical and surgical therapy, despite extensive infarction of the gastrointestinal tract and other organs. Prevention remains the most critical aspect of management of this potentially catastrophic illness.
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U2 - 10.1001/archinte.1989.00390100161035
DO - 10.1001/archinte.1989.00390100161035
M3 - Article
C2 - 2802904
AN - SCOPUS:0024459120
VL - 149
SP - 2371
EP - 2374
JO - Archives of internal medicine (Chicago, Ill. : 1908)
JF - Archives of internal medicine (Chicago, Ill. : 1908)
SN - 2168-6106
IS - 10
ER -