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Multi-Modal, Implantable Colon Activity Sensor

  • Steve J.A. Majerus
  • , Dario Cabal
  • , Yaneev Hacohen
  • , Brett Hanzlicek
  • , Aref Smiley
  • , Yushan Wang
  • , Wentai Liu
  • , Muriel Larauche
  • , Mulugeta Million
  • , Margot S. Damaser
  • , Dennis Bourbeau

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

Continuous monitoring of bowel activity during normal daily activities would improve clinical diagnostics and understanding the mechanisms underlying bowel function or help validate interventions that alter bowel function. This work describes a colon monitor to capture activity (ColoMOCA). The ColoMOCA included two pressure sensors, three impedance-sensing electrodes, and wireless battery recharge and data transmission circuitry. Components were integrated on a flexible printed circuit board, which was encapsulated in biocompatible silicone. Packaged ColoMOCAs were 8 mm in diameter and 85 mm long. ColoMOCAs continuously transmitted sensor data at 10Hz at 30 cm range, and ran for 21 hours before wireless recharge. Acute in vivo testing in conscious pigs demonstrated ColoMOCA detected colon phasic contractions with comparable accuracy relative to wired manometry sensors. Implantations of 7 days were performed which demonstrated conscious, ambulatory monitoring of colonic behavior, including phasic stool impedance data suggesting motility detection.

Original languageEnglish (US)
Title of host publication2022 IEEE Sensors, SENSORS 2022 - Conference Proceedings
PublisherInstitute of Electrical and Electronics Engineers Inc.
ISBN (Electronic)9781665484640
DOIs
StatePublished - 2022
Externally publishedYes
Event2022 IEEE Sensors Conference, SENSORS 2022 - Dallas, United States
Duration: Oct 30 2022Nov 2 2022

Publication series

NameProceedings of IEEE Sensors
Volume2022-October
ISSN (Print)1930-0395
ISSN (Electronic)2168-9229

Conference

Conference2022 IEEE Sensors Conference, SENSORS 2022
Country/TerritoryUnited States
CityDallas
Period10/30/2211/2/22

Keywords

  • biomedical electrodes
  • flexible electronics
  • implantable sensor
  • Pressure sensor
  • wireless device

ASJC Scopus subject areas

  • Electrical and Electronic Engineering

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