TY - JOUR
T1 - Multi-energy, single-isotope imaging using stacked detectors
AU - McDonald, B. S.
AU - Shokouhi, S.
AU - Barrett, H. H.
AU - Peterson, T. E.
N1 - Funding Information:
This work was supported by NIH Grants R33 EB000776-04 and P41 EB002035-07. The research of Todd E. Peterson, Ph.D. is supported in part by a Career Award at the Scientific Interface from the Burroughs Wellcome Fund.
PY - 2007/8/21
Y1 - 2007/8/21
N2 - We investigated a scheme for concurrently detecting low- and high-energy emissions from 123I with a stacked silicon double-sided strip detector (DSSD) and modular scintillation camera (Modcam) from the FastSPECT II design. We sequentially acquired both low- and high-energy emission images of an 123I object with a prototype DSSD and a Modcam. A sandwich aperture increases spatial resolution in the low-magnification DSSD image via a smaller pinhole diameter and allows a higher magnification image on the Modcam. Molybdenum, the insert material, efficiently stops 20-30 keV photons due to its ∼20 keV K-edge. Theoretically, less than 10% of 159 keV photons interact in 0.035 cm thick sheet of molybdenum, while this thickness stops virtually all ∼30 keV photons. Thus, photons from both energy regions will be incident upon their respective detectors with little cross talk. With a multi-pinhole collimator, we can decode multiplexed images on the Modcam by making use of the lower-magnification DSSD image. This approach can provide an increase in system sensitivity compared to single-detector configurations. Using MCNP5 we examined the potential benefits and drawbacks of stacked detectors and the sandwich aperture for small-animal pinhole SPECT via the synthetic-collimator method. Simulation results encourage us to construct the novel aperture and use it with our new DSSDs designed for mounting in a transmission configuration.
AB - We investigated a scheme for concurrently detecting low- and high-energy emissions from 123I with a stacked silicon double-sided strip detector (DSSD) and modular scintillation camera (Modcam) from the FastSPECT II design. We sequentially acquired both low- and high-energy emission images of an 123I object with a prototype DSSD and a Modcam. A sandwich aperture increases spatial resolution in the low-magnification DSSD image via a smaller pinhole diameter and allows a higher magnification image on the Modcam. Molybdenum, the insert material, efficiently stops 20-30 keV photons due to its ∼20 keV K-edge. Theoretically, less than 10% of 159 keV photons interact in 0.035 cm thick sheet of molybdenum, while this thickness stops virtually all ∼30 keV photons. Thus, photons from both energy regions will be incident upon their respective detectors with little cross talk. With a multi-pinhole collimator, we can decode multiplexed images on the Modcam by making use of the lower-magnification DSSD image. This approach can provide an increase in system sensitivity compared to single-detector configurations. Using MCNP5 we examined the potential benefits and drawbacks of stacked detectors and the sandwich aperture for small-animal pinhole SPECT via the synthetic-collimator method. Simulation results encourage us to construct the novel aperture and use it with our new DSSDs designed for mounting in a transmission configuration.
KW - I
KW - Monte Carlo
KW - Pinhole collimator
KW - SPECT
KW - Small-animal imaging
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U2 - 10.1016/j.nima.2007.04.142
DO - 10.1016/j.nima.2007.04.142
M3 - Article
AN - SCOPUS:34547653114
SN - 0168-9002
VL - 579
SP - 196
EP - 199
JO - Nuclear Instruments and Methods in Physics Research, Section A: Accelerators, Spectrometers, Detectors and Associated Equipment
JF - Nuclear Instruments and Methods in Physics Research, Section A: Accelerators, Spectrometers, Detectors and Associated Equipment
IS - 1
ER -