Mucinous adenocarcinoma of the endometrium with intestinal differentiation: A case report

Wenxin Zheng, Grace C.H. Yang, Thomas A. Godwin, Thomas A. Caputo, Rosemary E. Zuna

Research output: Contribution to journalArticlepeer-review

36 Scopus citations


Mucinous differentiation of endocervical type has been well documented in endometrial carcinoma. However, we describe an unusual case of adenocarcinoma of the endometrium showing diffuse histological, immunohistochemical, and ultrastructural evidence of intestinal differentiation. Although intestinal differentiation has been described in mesodermally derived tissues including endocervix, ovary, and urinary tract, it has not been reported in normal endometrium. One previous case has been reported showing this pattern in endometrial carcinoma. Possible histogenetic mechanisms of this pattern are discussed.

Original languageEnglish (US)
Pages (from-to)1385-1388
Number of pages4
JournalHuman pathology
Issue number12
StatePublished - Dec 1995
Externally publishedYes


  • endometrial carcinoma
  • intestinal differentiation
  • intestinal metaplasia
  • neuroendocrine differentiation

ASJC Scopus subject areas

  • Pathology and Forensic Medicine


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