MRI intensity nonuniformity correction using simultaneously spatial and gray-level histogram information

Julien Milles, Yue Min Zhu, Nankuei Chen, Lawrence P. Panych, Gérard Gimenez, Charles R.G. Guttmann

Research output: Contribution to journalConference articlepeer-review

9 Scopus citations


A novel approach for correcting intensity nonuniformity in magnetic resonance imaging (MRI) is presented. This approach is based on the fusion of spatial and gray-level histogram information. Spatial information about intensity nonuniformity is obtained using cubic B-spline smoothing. Gray-level histogram information of the image corrupted by intensity nonuniformity is exploited from a frequential point of view. The proposed correction method is illustrated using both physical phantom and human brain images. The results are consistent with theoretical prediction, and demonstrate a new way of dealing with intensity nonuniformity problems.

Original languageEnglish (US)
Pages (from-to)734-742
Number of pages9
JournalProceedings of SPIE - The International Society for Optical Engineering
Volume5370 II
StatePublished - 2004
Externally publishedYes
EventProgress in Biomedical Optics and Imaging - Medical Imaging 2004: Imaging Processing - San Diego, CA, United States
Duration: Feb 16 2004Feb 19 2004


  • Brain
  • Correction
  • Intensity nonuniformity
  • Magnetic resonance imaging

ASJC Scopus subject areas

  • Electronic, Optical and Magnetic Materials
  • Condensed Matter Physics
  • Computer Science Applications
  • Applied Mathematics
  • Electrical and Electronic Engineering


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