TY - GEN
T1 - Molecular imaging in the College of Optical Sciences
T2 - 50 Years of Optical Sciences at the University of Arizona
AU - Furenlid, Lars R.
AU - Barrett, Harrison H.
AU - Barber, H. Bradford
AU - Clarkson, Eric W.
AU - Kupinski, Matthew A.
AU - Liu, Zhonglin
AU - Stevenson, Gail D.
AU - Woolfenden, James M.
N1 - Publisher Copyright:
© 2014 SPIE.
PY - 2014
Y1 - 2014
N2 - During the past two decades, researchers at the University of Arizona's Center for Gamma-Ray Imaging (CGRI) have explored a variety of approaches to gamma-ray detection, including scintillation cameras, solid-state detectors, and hybrids such as the intensified Quantum Imaging Device (iQID) configuration where a scintillator is followed by optical gain and a fast CCD or CMOS camera. We have combined these detectors with a variety of collimation schemes, including single and multiple pinholes, parallel-hole collimators, synthetic apertures, and anamorphic crossed slits, to build a large number of preclinical molecular-imaging systems that perform Single-Photon Emission Computed Tomography (SPECT), Positron Emission Tomography (PET), and X-Ray Computed Tomography (CT). In this paper, we discuss the themes and methods we have developed over the years to record and fully use the information content carried by every detected gamma-ray photon.
AB - During the past two decades, researchers at the University of Arizona's Center for Gamma-Ray Imaging (CGRI) have explored a variety of approaches to gamma-ray detection, including scintillation cameras, solid-state detectors, and hybrids such as the intensified Quantum Imaging Device (iQID) configuration where a scintillator is followed by optical gain and a fast CCD or CMOS camera. We have combined these detectors with a variety of collimation schemes, including single and multiple pinholes, parallel-hole collimators, synthetic apertures, and anamorphic crossed slits, to build a large number of preclinical molecular-imaging systems that perform Single-Photon Emission Computed Tomography (SPECT), Positron Emission Tomography (PET), and X-Ray Computed Tomography (CT). In this paper, we discuss the themes and methods we have developed over the years to record and fully use the information content carried by every detected gamma-ray photon.
KW - CT
KW - PET
KW - SPECT
KW - collimation
KW - detectors
KW - estimation
KW - instrumentation
KW - molecular imaging
KW - reconstruction
UR - http://www.scopus.com/inward/record.url?scp=84937843585&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84937843585&partnerID=8YFLogxK
U2 - 10.1117/12.2064808
DO - 10.1117/12.2064808
M3 - Conference contribution
AN - SCOPUS:84937843585
T3 - Proceedings of SPIE - The International Society for Optical Engineering
BT - Fifty Years of Optical Sciences at the University of Arizona
A2 - Greivenkamp, John E.
A2 - Dereniak, Eustace L.
A2 - Barrett, Harrison H.
PB - SPIE
Y2 - 19 August 2014 through 20 August 2014
ER -