Molecular catch and release: Controlled delivery using optical trapping with light-responsive liposomes

Sarah J. Leung; Marek Romanowski

doi:10.1002/adma.201202180

Molecular catch and release: Controlled delivery using optical trapping with light-responsive liposomes

Sarah J. Leung, Marek Romanowski

Research output: Contribution to journal › Article › peer-review

28 Scopus citations

Abstract

Gold-coated liposomes are maneuvered using an optical trap to achieve precise delivery of encapsulated molecular cargo. Movement and payload release from these plasmon resonant nanocapsules are independently controlled using a pulsed trapping beam. This technology enables in vitro delivery of a payload to a selected cell and may be applied to the interrogation of individual cells within their biological microenvironment.

Original language	English (US)
Pages (from-to)	6380-6383
Number of pages	4
Journal	Advanced Materials
Volume	24
Issue number	47
DOIs	https://doi.org/10.1002/adma.201202180
State	Published - Dec 11 2012

Keywords

controlled release
liposomes
nanoparticles
optical trapping
plasmon resonance

ASJC Scopus subject areas

General Materials Science
Mechanics of Materials
Mechanical Engineering

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10.1002/adma.201202180

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abstract = "Gold-coated liposomes are maneuvered using an optical trap to achieve precise delivery of encapsulated molecular cargo. Movement and payload release from these plasmon resonant nanocapsules are independently controlled using a pulsed trapping beam. This technology enables in vitro delivery of a payload to a selected cell and may be applied to the interrogation of individual cells within their biological microenvironment.",

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AB - Gold-coated liposomes are maneuvered using an optical trap to achieve precise delivery of encapsulated molecular cargo. Movement and payload release from these plasmon resonant nanocapsules are independently controlled using a pulsed trapping beam. This technology enables in vitro delivery of a payload to a selected cell and may be applied to the interrogation of individual cells within their biological microenvironment.

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KW - nanoparticles

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KW - plasmon resonance

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Molecular catch and release: Controlled delivery using optical trapping with light-responsive liposomes

Abstract

Keywords

ASJC Scopus subject areas

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