@article{63a9cf00f91a4a02b49c074f21f335ad,
title = "Modifications op the 4,4'-residues and SAR studies of Biphalin, a highly potent opioid receptor active peptide",
abstract = "Modifications of 4,4' residues of Biphalin have resulted in greater binding selectivity and biological potency for the μ opioid receptor. A higher partition coefficient across the phospholipid bilayer membrane has been achieved by using a β-branched unusual amino acids.",
author = "Guigen Li and W. Haq and Li Xiang and Lou, \{Bih Show\} and Robert Hughes and \{De Leon\}, \{Irene A.\} and Peg Davis and Gillespie, \{Terrence J.\} and Marek Romanowski and Zhu Xiaoyun and Aleksandra Misicka and Lipkowski, \{Andrzej W.\} and Frank Porreca and Davis, \{Thomas P.\} and Yamamura, \{Henry I.\} and O'Brien, \{David F.\} and Hruby, \{Victor J.\}",
note = "Funding Information: This work was supported by U. S. Public Service Grant NS 19972, by NIDA Grant DA 06284, and by a 1994 Research Fellowship to G. Li (Graduate College, University of Arizona).",
year = "1998",
month = mar,
day = "3",
doi = "10.1016/S0960-894X(98)00065-1",
language = "English (US)",
volume = "8",
pages = "555--560",
journal = "Bioorganic and Medicinal Chemistry Letters",
issn = "0960-894X",
publisher = "Elsevier Ltd",
number = "5",
}