Mobile genetic elements in the genus bacteroides, and their mechanism(s) of dissemination

Mai Nguyen, Gayatri Vedantam

Research output: Chapter in Book/Report/Conference proceedingChapter

Abstract

Bacteroides spp organisms, the predominant commensal bacteria in the human gut have become increasingly resistant to many antibiotics. They are now also considered to be reservoirs of antibiotic resistance genes due to their capacity to harbor and disseminate these genes via mobile transmissible elements that occur in bewildering variety. Gene dissemination occurs within and from Bacteroides spp primarily by conjugation, the molecular mechanisms of which are stül poorly understood in the genus, even though the need to prevent this dissemination is urgent. One current avenue of research is thus focused on interventions that use non-antibiotic methodologies to prevent conjugation-based DNA transfer.

Original languageEnglish (US)
Title of host publicationBacterial Integrative Mobile Genetic Elements
PublisherCRC Press
Pages104-119
Number of pages16
ISBN (Electronic)9781000716887
ISBN (Print)9781587066603
DOIs
StatePublished - Mar 8 2022

ASJC Scopus subject areas

  • General Agricultural and Biological Sciences
  • General Biochemistry, Genetics and Molecular Biology
  • General Medicine

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