Mitral valve area in combined mitral stenosis and regurgitation

J. Askenazi, C. J. Carlson, J. S. Alpert, L. Dexter

Research output: Contribution to journalArticlepeer-review

9 Scopus citations


8 Patients with mixed mitral stenosis and regurgitation underwent hemodynamic and angiographic study prior to mitral valve replacement. The stenotic orifice of the mitral valve was calculated employing the total left ventricular stroke volume by cineangiography as the numerator of the Gorlin formula. Excellent agreement with the measured orifice of the mitral valve was obtained using a value of 37.9 (0.85 x 44.5) for the constant in the Gorlin formula as recommended by Cohen and Gorlin. Recalculation of this constant independently by the data yielded a value that was almost identical. Regurgitation flows and orifice were calculated for each patient using the same constant as for calculation of the stenotic orifices.

Original languageEnglish (US)
Pages (from-to)480-483
Number of pages4
Issue number3
StatePublished - 1976

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine
  • Physiology (medical)


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