Mitogauzone, cisplatin, and vinblastine in advanced non-small cell lung cancer: A Southwest Oncology Group study

Robert Chapman; John Crowley; Joel G. Lucas; Ben Lin Hom; Robert B. Livingston; Clarence B. Vaughn; Harry E. Hynes

doi:10.1007/BF00873920

Mitogauzone, cisplatin, and vinblastine in advanced non-small cell lung cancer: A Southwest Oncology Group study

Robert Chapman, John Crowley, Joel G. Lucas, Ben Lin Hom, Robert B. Livingston, Clarence B. Vaughn, Harry E. Hynes

Research output: Contribution to journal › Article › peer-review

Abstract

This trial employing MGBG, vinblastine, and cisplatin in patients with advanced NSCLC produced a 10% response rate with no durable responses. This is disappointing compared to previously cited studies, although the median overall survival of 7.0 months is comparable. The relatively mild toxicity noted in this trial suggests that more aggressive use of the same combination may be feasible.

Original language	English (US)
Pages (from-to)	91-92
Number of pages	2
Journal	Investigational New Drugs
Volume	11
Issue number	1
DOIs	https://doi.org/10.1007/BF00873920
State	Published - Feb 1993
Externally published	Yes

Keywords

cisplatin
mitogauzone
vinblastine

ASJC Scopus subject areas

Oncology
Pharmacology
Pharmacology (medical)

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10.1007/BF00873920

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abstract = "This trial employing MGBG, vinblastine, and cisplatin in patients with advanced NSCLC produced a 10% response rate with no durable responses. This is disappointing compared to previously cited studies, although the median overall survival of 7.0 months is comparable. The relatively mild toxicity noted in this trial suggests that more aggressive use of the same combination may be feasible.",

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AU - Vaughn, Clarence B.

AU - Hynes, Harry E.

PY - 1993/2

Y1 - 1993/2

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KW - vinblastine

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Mitogauzone, cisplatin, and vinblastine in advanced non-small cell lung cancer: A Southwest Oncology Group study

Abstract

Keywords

ASJC Scopus subject areas

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