Miscalculated lung shunt fraction for planning of hepatic radioembolization

Justin S. Caskey; Matthew D. Kay; Natalie A. McMillan; Phillip H. Kuo; Gregory J. Woodhead

doi:10.2967/jnmt.119.234385

Miscalculated lung shunt fraction for planning of hepatic radioembolization

Justin S. Caskey, Matthew D. Kay, Natalie A. McMillan, Phillip H. Kuo, Gregory J. Woodhead

Research output: Contribution to journal › Article › peer-review

1 Scopus citations

Abstract

90Y radioembolization is a safe and efficacious treatment option for many patients with unresectable hepatocellular carcinoma. Potential candidates for radioembolization, based on clinical criteria, undergo 99mTc-labeled macroaggregated albumin imaging to determine the extent of hepatopulmonary shunting. Dose selection is based on results from shunt imaging and can exclude patients from radioembolization therapy. We present a case of miscalculated lung shunt fraction and the circumstances that led to the critical error.

Original language	English (US)
Pages (from-to)	184-186
Number of pages	3
Journal	Journal of nuclear medicine technology
Volume	48
Issue number	2
DOIs	https://doi.org/10.2967/jnmt.119.234385
State	Published - Jun 1 2020

Keywords

Hepatocellular carcinoma
Lung shunt fraction
Tc-labeled macroaggregated albumin
Y radioembolization

ASJC Scopus subject areas

General Medicine

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10.2967/jnmt.119.234385

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abstract = "90Y radioembolization is a safe and efficacious treatment option for many patients with unresectable hepatocellular carcinoma. Potential candidates for radioembolization, based on clinical criteria, undergo 99mTc-labeled macroaggregated albumin imaging to determine the extent of hepatopulmonary shunting. Dose selection is based on results from shunt imaging and can exclude patients from radioembolization therapy. We present a case of miscalculated lung shunt fraction and the circumstances that led to the critical error.",

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AU - Caskey, Justin S.

AU - Kay, Matthew D.

AU - McMillan, Natalie A.

AU - Kuo, Phillip H.

AU - Woodhead, Gregory J.

PY - 2020/6/1

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AB - 90Y radioembolization is a safe and efficacious treatment option for many patients with unresectable hepatocellular carcinoma. Potential candidates for radioembolization, based on clinical criteria, undergo 99mTc-labeled macroaggregated albumin imaging to determine the extent of hepatopulmonary shunting. Dose selection is based on results from shunt imaging and can exclude patients from radioembolization therapy. We present a case of miscalculated lung shunt fraction and the circumstances that led to the critical error.

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KW - Tc-labeled macroaggregated albumin

KW - Y radioembolization

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Miscalculated lung shunt fraction for planning of hepatic radioembolization

Abstract

Keywords

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