TY - JOUR
T1 - Minor and Trace Sterols in Marine Invertebrates. 26.1 Isolation and Structure Elucidation of Nine New 5α,8α-Epidioxy Sterols from Four Marine Organisms
AU - Leslie Gunatilaka, A. A.
AU - Gopichand, Yalamanchili
AU - Schmitz, Francis J.
AU - Djerassi, Carl
PY - 1981/9
Y1 - 1981/9
N2 - Sixteen 5α,8α-epidioxy ∆6 and ∆6,9(11) sterols, of which nine are new, have been isolated from the marine organisms Ascidia nigra, Dendrogyra cylindrus, Thalysias juniperina, and Aplysia dactyLornela by reverse-phase highperformance liquid chromatography and characterized by high-resolution mass spectrometry and 360-MHz proton NMR spectroscopy. Attention is drawn to some unusual concentration-dependent NMR shifts of methyl signals. The probable biological significance of these epidioxy sterols is discussed with special reference to sterol biosynthesis.
AB - Sixteen 5α,8α-epidioxy ∆6 and ∆6,9(11) sterols, of which nine are new, have been isolated from the marine organisms Ascidia nigra, Dendrogyra cylindrus, Thalysias juniperina, and Aplysia dactyLornela by reverse-phase highperformance liquid chromatography and characterized by high-resolution mass spectrometry and 360-MHz proton NMR spectroscopy. Attention is drawn to some unusual concentration-dependent NMR shifts of methyl signals. The probable biological significance of these epidioxy sterols is discussed with special reference to sterol biosynthesis.
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U2 - 10.1021/jo00332a020
DO - 10.1021/jo00332a020
M3 - Article
AN - SCOPUS:0001679909
SN - 0022-3263
VL - 46
SP - 3860
EP - 3866
JO - Journal of Organic Chemistry
JF - Journal of Organic Chemistry
IS - 19
ER -