Abstract
Utilization of a miniaturized handheld stimulated Raman scattering (SRS) microscope versus a benchtop SRS microscope presents greater flexibility for in vivo chemical imaging and medical diagnosis in human subjects. This chapter reviews a state-of-the-art background-free fiber-delivered handheld SRS microscope, including its design principle, technical challenges, and biomedical applications. In the end, we outlook the pathways to improve the handheld SRS microscope for clinical applications.
| Original language | English (US) |
|---|---|
| Title of host publication | Stimulated Raman Scattering Microscopy |
| Subtitle of host publication | Techniques and Applications |
| Publisher | Elsevier |
| Pages | 551-560 |
| Number of pages | 10 |
| ISBN (Electronic) | 9780323851589 |
| ISBN (Print) | 9780323903370 |
| DOIs | |
| State | Published - Jan 1 2021 |
Keywords
- Handheld microscopes
- Intraoperative imaging
- Miniature objective lens
- Nonlinear optical background
- Stimulated raman scattering
ASJC Scopus subject areas
- General Chemistry
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