Miniaturized handheld stimulated Raman scattering microscope

Peng Lin, Hongli Ni, Chien Sheng Liao, Rongguang Liang, Ji Xin Cheng

Research output: Chapter in Book/Report/Conference proceedingChapter


Utilization of a miniaturized handheld stimulated Raman scattering (SRS) microscope versus a benchtop SRS microscope presents greater flexibility for in vivo chemical imaging and medical diagnosis in human subjects. This chapter reviews a state-of-the-art background-free fiber-delivered handheld SRS microscope, including its design principle, technical challenges, and biomedical applications. In the end, we outlook the pathways to improve the handheld SRS microscope for clinical applications.

Original languageEnglish (US)
Title of host publicationStimulated Raman Scattering Microscopy
Subtitle of host publicationTechniques and Applications
Number of pages10
ISBN (Electronic)9780323851589
ISBN (Print)9780323903370
StatePublished - Jan 1 2021


  • Handheld microscopes
  • Intraoperative imaging
  • Miniature objective lens
  • Nonlinear optical background
  • Stimulated raman scattering

ASJC Scopus subject areas

  • Chemistry(all)


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