Mild and convenient oxidation of aromatic heterocyclic primary alcohols by 4-acetylamino-2,2,6,6-tetramethylpiperidine-1-oxoammonium perchlorate

Casey A. Kernag; James M. Bobbitt; Dominic V. McGrath

doi:10.1016/S0040-4039(99)00029-5

Mild and convenient oxidation of aromatic heterocyclic primary alcohols by 4-acetylamino-2,2,6,6-tetramethylpiperidine-1-oxoammonium perchlorate

Casey A. Kernag, James M. Bobbitt, Dominic V. McGrath

Research output: Contribution to journal › Article › peer-review

24 Scopus citations

Abstract

Hydroxymethyl substituted aromatic heterocycles, including pyridines, furans, and thiophenes, are oxidized to the corresponding aldehydes in excellent yields by 4-acetylamino-2,2,6,6-tetramethylpiperidine-1- oxoammonium perchlorate (1) with minimal workup.

Original language	English (US)
Pages (from-to)	1635-1636
Number of pages	2
Journal	Tetrahedron Letters
Volume	40
Issue number	9
DOIs	https://doi.org/10.1016/S0040-4039(99)00029-5
State	Published - Feb 26 1999

ASJC Scopus subject areas

Biochemistry
Drug Discovery
Organic Chemistry

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title = "Mild and convenient oxidation of aromatic heterocyclic primary alcohols by 4-acetylamino-2,2,6,6-tetramethylpiperidine-1-oxoammonium perchlorate",

abstract = "Hydroxymethyl substituted aromatic heterocycles, including pyridines, furans, and thiophenes, are oxidized to the corresponding aldehydes in excellent yields by 4-acetylamino-2,2,6,6-tetramethylpiperidine-1- oxoammonium perchlorate (1) with minimal workup.",

author = "Kernag, {Casey A.} and Bobbitt, {James M.} and McGrath, {Dominic V.}",

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T1 - Mild and convenient oxidation of aromatic heterocyclic primary alcohols by 4-acetylamino-2,2,6,6-tetramethylpiperidine-1-oxoammonium perchlorate

AU - Kernag, Casey A.

AU - Bobbitt, James M.

AU - McGrath, Dominic V.

PY - 1999/2/26

Y1 - 1999/2/26

N2 - Hydroxymethyl substituted aromatic heterocycles, including pyridines, furans, and thiophenes, are oxidized to the corresponding aldehydes in excellent yields by 4-acetylamino-2,2,6,6-tetramethylpiperidine-1- oxoammonium perchlorate (1) with minimal workup.

AB - Hydroxymethyl substituted aromatic heterocycles, including pyridines, furans, and thiophenes, are oxidized to the corresponding aldehydes in excellent yields by 4-acetylamino-2,2,6,6-tetramethylpiperidine-1- oxoammonium perchlorate (1) with minimal workup.

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U2 - 10.1016/S0040-4039(99)00029-5

DO - 10.1016/S0040-4039(99)00029-5

M3 - Article

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JO - Tetrahedron Letters

JF - Tetrahedron Letters

IS - 9

ER -

Mild and convenient oxidation of aromatic heterocyclic primary alcohols by 4-acetylamino-2,2,6,6-tetramethylpiperidine-1-oxoammonium perchlorate

Abstract

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