Microwave-assisted three-component Knoevenagel-nucleophilic aromatic substitution reactions

Hui Xu, Xinhong Yu, Leying Sun, Jing Liu, Wen Fan, Yongjia Shen, Wei Wang

Research output: Contribution to journalArticlepeer-review

14 Scopus citations

Abstract

A powerful microwave-assisted three-component Knoevenagel-nucleophilic aromatic substitution reaction of 4-halobenzaldehydes, cyanoacetatic acid esters/cyanoacetamides, and cyclic secondary amines has been developed.

Original languageEnglish (US)
Pages (from-to)4687-4689
Number of pages3
JournalTetrahedron Letters
Volume49
Issue number32
DOIs
StatePublished - Aug 4 2008
Externally publishedYes

Keywords

  • 4-Halobenzaldehyde
  • Microwave-assisted reaction
  • SAr
  • Three-component reaction

ASJC Scopus subject areas

  • Biochemistry
  • Drug Discovery
  • Organic Chemistry

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