Abstract
Biotransformation of 16α,17-epoxy-ent-kaurane-19-oic acid (1) by Beauveria sulfurescens ATCC 7159-F led to the production of a new ent-kaurane diterpenoid, 7β,17-dihydroxy-ent-kaur-15-en-19-oic acid (7), and four other ent-kauranes (8 - 11), all of which were identified as their methyl esters. Compounds 9 and 10 were found to be new stereoisomers. Structures of these were established by the extensive usage of their spectroscopic characteristics.
Original language | English (US) |
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Pages (from-to) | 1041-1044 |
Number of pages | 4 |
Journal | Natural Product Communications |
Volume | 8 |
Issue number | 8 |
State | Published - Aug 2013 |
Keywords
- Beauveria sulfurescens
- Biotransformation
- Ent-kauranes
- Structure elucidation
ASJC Scopus subject areas
- Pharmacology
- Drug Discovery
- Plant Science
- Complementary and alternative medicine