Metabolism of limonene-1,2-epoxide in the rat

J. W. Regan; M. M. Morris; B. Nao; L. F. Bjeldanes

doi:10.3109/00498258009033819

Metabolism of limonene-1,2-epoxide in the rat

J. W. Regan, M. M. Morris, B. Nao, L. F. Bjeldanes

Research output: Contribution to journal › Article › peer-review

5 Scopus citations

Abstract

1. The metabolism of limonene-1,2-epoxide was studied following intraperitoneal injection in rats and in rat liver homogenates. 2. Limonene-1,2-glycol was the only neutral metabolite detected. Major limonene metabolites, mentha-2,8-dien-1-α and -ol and mentha-1,8-dien-6-α and -ol were not observed. 3. Limonene-1,2-epoxide is not a major intermediate in limonene metabolism in the rat.

Original language	English (US)
Pages (from-to)	859-861
Number of pages	3
Journal	Xenobiotica
Volume	10
Issue number	12
DOIs	https://doi.org/10.3109/00498258009033819
State	Published - 1980
Externally published	Yes

ASJC Scopus subject areas

Biochemistry
Toxicology
Pharmacology
Health, Toxicology and Mutagenesis

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title = "Metabolism of limonene-1,2-epoxide in the rat",

abstract = "1. The metabolism of limonene-1,2-epoxide was studied following intraperitoneal injection in rats and in rat liver homogenates. 2. Limonene-1,2-glycol was the only neutral metabolite detected. Major limonene metabolites, mentha-2,8-dien-1-α and -ol and mentha-1,8-dien-6-α and -ol were not observed. 3. Limonene-1,2-epoxide is not a major intermediate in limonene metabolism in the rat.",

author = "Regan, {J. W.} and Morris, {M. M.} and B. Nao and Bjeldanes, {L. F.}",

note = "Funding Information: This research was supported by the California Agricultural Experiment Station.",

year = "1980",

doi = "10.3109/00498258009033819",

language = "English (US)",

volume = "10",

pages = "859--861",

journal = "Xenobiotica",

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T1 - Metabolism of limonene-1,2-epoxide in the rat

AU - Regan, J. W.

AU - Morris, M. M.

AU - Nao, B.

AU - Bjeldanes, L. F.

N1 - Funding Information: This research was supported by the California Agricultural Experiment Station.

PY - 1980

Y1 - 1980

N2 - 1. The metabolism of limonene-1,2-epoxide was studied following intraperitoneal injection in rats and in rat liver homogenates. 2. Limonene-1,2-glycol was the only neutral metabolite detected. Major limonene metabolites, mentha-2,8-dien-1-α and -ol and mentha-1,8-dien-6-α and -ol were not observed. 3. Limonene-1,2-epoxide is not a major intermediate in limonene metabolism in the rat.

AB - 1. The metabolism of limonene-1,2-epoxide was studied following intraperitoneal injection in rats and in rat liver homogenates. 2. Limonene-1,2-glycol was the only neutral metabolite detected. Major limonene metabolites, mentha-2,8-dien-1-α and -ol and mentha-1,8-dien-6-α and -ol were not observed. 3. Limonene-1,2-epoxide is not a major intermediate in limonene metabolism in the rat.

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EP - 861

JO - Xenobiotica

JF - Xenobiotica

IS - 12

ER -

Metabolism of limonene-1,2-epoxide in the rat

Abstract

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