@article{60698fba75714989ba5e68c7b788d822,
title = "Merging Visible Light with Cross-Coupling: The Photochemical Direct C-H Difluoroalkylation of Imidazopyridines",
abstract = "A transition-metal-free protocol for the difluoroalkylation of imidazopyridines with bromodifluoroaryl ketones promoted by visible light irradiation is presented. This protocol is distinguished by simple, mild, and catalyst-free reaction conditions with a wide reaction scope, which is complementary to existing difluoroalkylation strategies by photoredox scenarios. Additionally, this protocol potentially offers a new way for streamlining the synthesis of compounds containing the difluoro moiety.",
author = "Qu, {Chuan Hua} and Song, {Gui Ting} and Jia Xu and Wei Yan and Zhou, {Cheng He} and Li, {Hong Yu} and Chen, {Zhong Zhu} and Xu, {Zhi Gang}",
note = "Funding Information: The authors thank the Science and Technology Research Program of Chongqing Municipal Education Commission (KJZH17129, KJQN201801321, KJZD-M201801301), the Natural Science Foundation Project of CQ CSTSC (CSTC2015ZDCY-ZTZX120003, cstc2018jszx-cyzd0110, and cstc2018jszx-cyzdX0023), and the Scientific Research Foundation of the Chongqing Univ. of Arts and Sciences (Z2016BX02). We also thank Ms. H. Z. Liu of Chongqing Univ. of Arts and Sciences for obtaining the LC/MS, HRMS, and NMR data. Publisher Copyright: Copyright {\textcopyright} 2019 American Chemical Society.",
year = "2019",
month = oct,
day = "18",
doi = "10.1021/acs.orglett.9b02487",
language = "English (US)",
volume = "21",
pages = "8169--8173",
journal = "Organic Letters",
issn = "1523-7060",
publisher = "American Chemical Society",
number = "20",
}