Melanocortinergic control of penile erection

H. Wessells; J. E. Blevins; T. W. Vanderah

doi:10.1016/j.peptides.2004.11.035

Melanocortinergic control of penile erection

H. Wessells, J. E. Blevins, T. W. Vanderah

Research output: Contribution to journal › Review article › peer-review

22 Scopus citations

Abstract

Melanocortin receptors in the forebrain and spinal cord can be activated by endogenous or synthetic ligands to induce penile erection in rats and human subjects. To better understand how melanocortin circuits play a role in sex behavior, we review the contribution of melanocortin receptors and/or neurons in the hypothalamus, hindbrain, spinal cord and peripheral nerves to erectile function. New information regarding neuropeptides that mediate penile erection has extended our understanding of the central control of sex behavior, and melanocortin agonists may provide alternatives to existing treatment for highly prevalent problems including erectile dysfunction.

Original language	English (US)
Pages (from-to)	1972-1977
Number of pages	6
Journal	Peptides
Volume	26
Issue number	10
DOIs	https://doi.org/10.1016/j.peptides.2004.11.035
State	Published - Oct 2005

Keywords

Hindbrain
MSH
Proopiomelanocortin
Sex behavior

ASJC Scopus subject areas

Biochemistry
Physiology
Endocrinology
Cellular and Molecular Neuroscience

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10.1016/j.peptides.2004.11.035

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title = "Melanocortinergic control of penile erection",

abstract = "Melanocortin receptors in the forebrain and spinal cord can be activated by endogenous or synthetic ligands to induce penile erection in rats and human subjects. To better understand how melanocortin circuits play a role in sex behavior, we review the contribution of melanocortin receptors and/or neurons in the hypothalamus, hindbrain, spinal cord and peripheral nerves to erectile function. New information regarding neuropeptides that mediate penile erection has extended our understanding of the central control of sex behavior, and melanocortin agonists may provide alternatives to existing treatment for highly prevalent problems including erectile dysfunction.",

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author = "H. Wessells and Blevins, {J. E.} and Vanderah, {T. W.}",

year = "2005",

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T1 - Melanocortinergic control of penile erection

AU - Wessells, H.

AU - Blevins, J. E.

AU - Vanderah, T. W.

PY - 2005/10

Y1 - 2005/10

N2 - Melanocortin receptors in the forebrain and spinal cord can be activated by endogenous or synthetic ligands to induce penile erection in rats and human subjects. To better understand how melanocortin circuits play a role in sex behavior, we review the contribution of melanocortin receptors and/or neurons in the hypothalamus, hindbrain, spinal cord and peripheral nerves to erectile function. New information regarding neuropeptides that mediate penile erection has extended our understanding of the central control of sex behavior, and melanocortin agonists may provide alternatives to existing treatment for highly prevalent problems including erectile dysfunction.

AB - Melanocortin receptors in the forebrain and spinal cord can be activated by endogenous or synthetic ligands to induce penile erection in rats and human subjects. To better understand how melanocortin circuits play a role in sex behavior, we review the contribution of melanocortin receptors and/or neurons in the hypothalamus, hindbrain, spinal cord and peripheral nerves to erectile function. New information regarding neuropeptides that mediate penile erection has extended our understanding of the central control of sex behavior, and melanocortin agonists may provide alternatives to existing treatment for highly prevalent problems including erectile dysfunction.

KW - Hindbrain

KW - MSH

KW - Proopiomelanocortin

KW - Sex behavior

UR - http://www.scopus.com/inward/record.url?scp=25144508009&partnerID=8YFLogxK

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DO - 10.1016/j.peptides.2004.11.035

M3 - Review article

C2 - 15992962

AN - SCOPUS:25144508009

SN - 0196-9781

VL - 26

SP - 1972

EP - 1977

JO - Peptides

JF - Peptides

IS - 10

ER -

Melanocortinergic control of penile erection

Abstract

Keywords

ASJC Scopus subject areas

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