Mechanism of action of retinyl compounds on wound healing II: Effect of active retinyl derivatives on granuloma formation

The naturally occurring retinyl derivatives that promote wound healing as measured by their effects on tensile strength of healing wounds also stimulate granuloma formation induced by cotton pellets. The hexosamine and hydroxyproline contents in the granuloma affected by retinyl derivatives are also increased. The mechanisms of action of retinyl derivation on wound healing are discussed.