Mechanics of shear stress transmission to endothelial cells in blood vessels lined with an endothelial surface layer

Timothy W. Secomb, Axel R. Pries

Research output: Contribution to journalConference articlepeer-review

4 Scopus citations

Abstract

Mechanics of shear stress transmission to endothelial cells in blood vessels lined with an endothelial surface layer (ESL) was studied. Both flat and wavy surfaces were considered as endothelial surfaces in arteries are non-uniform, with bulges corresponding to endothelial cell nuclei. Results showed that at the surface peaks, shear stress was higher and the ESL was thinner.

Original languageEnglish (US)
Pages (from-to)389-390
Number of pages2
JournalAmerican Society of Mechanical Engineers, Bioengineering Division (Publication) BED
Volume50
StatePublished - 2001
EventProceedings of the 2001 Bioengineering Conference - Snowbird, UT, United States
Duration: Jun 27 2001Jul 1 2001

ASJC Scopus subject areas

  • General Engineering

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