Abstract
At sites of damage DNA is resected to enable the optimal form of repair, directed by homology. But how does the cell regulate resection while coordinating with the cell cycle? In this issue of The EMBO Journal, Clerici et al define missing links between DNA resection and cell cycle arrest during repair, showing that Mec1 can inhibit resection to subsequently activate arrest by Tel1.
Original language | English (US) |
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Pages (from-to) | 176-178 |
Number of pages | 3 |
Journal | EMBO Journal |
Volume | 33 |
Issue number | 3 |
DOIs | |
State | Published - Feb 3 2014 |
Externally published | Yes |
ASJC Scopus subject areas
- General Neuroscience
- Molecular Biology
- General Biochemistry, Genetics and Molecular Biology
- General Immunology and Microbiology