TY - JOUR
T1 - Measures to evaluate the effects of DBS on speech production
AU - Weismer, Gary
AU - Yunusova, Yana
AU - Bunton, Kate
N1 - Funding Information:
The work reported here, and specifically the research reported in Section 4.2.4 , was supported by a grant from the National Institutes of Health (NIH) , “Articulatory Kinematics in Neurogenic Speech Disorders” (Award # R01 DC 003723 , G. Weismer, Principal Investigator). John Westbury designed the measure of phonetic working space described in this paper, and Clarissa Weiss assisted in data analysis.
PY - 2012/3
Y1 - 2012/3
N2 - The purpose of this paper is to review and evaluate measures of speech production that could be used to document effects of Deep Brain Stimulation (DBS) on speech performance, especially in persons with Parkinson disease (PD). A small set of evaluative criteria for these measures is presented first, followed by consideration of several speech physiology and speech acoustic measures that have been studied frequently and reported on in the literature on normal speech production, and speech production affected by neuromotor disorders (dysarthria). Each measure is reviewed and evaluated against the evaluative criteria. Embedded within this review and evaluation is a presentation of new data relating speech motions to speech intelligibility measures in speakers with PD, amyotrophic lateral sclerosis (ALS), and control speakers (CS). These data are used to support the conclusion that at the present time the slope of second formant transitions (F2 slope), an acoustic measure, is well suited to make inferences to speech motion and to predict speech intelligibility. The use of other measures should not be ruled out, however, and we encourage further development of evaluative criteria for speech measures designed to probe the effects of DBS or any treatment with potential effects on speech production and communication skills.
AB - The purpose of this paper is to review and evaluate measures of speech production that could be used to document effects of Deep Brain Stimulation (DBS) on speech performance, especially in persons with Parkinson disease (PD). A small set of evaluative criteria for these measures is presented first, followed by consideration of several speech physiology and speech acoustic measures that have been studied frequently and reported on in the literature on normal speech production, and speech production affected by neuromotor disorders (dysarthria). Each measure is reviewed and evaluated against the evaluative criteria. Embedded within this review and evaluation is a presentation of new data relating speech motions to speech intelligibility measures in speakers with PD, amyotrophic lateral sclerosis (ALS), and control speakers (CS). These data are used to support the conclusion that at the present time the slope of second formant transitions (F2 slope), an acoustic measure, is well suited to make inferences to speech motion and to predict speech intelligibility. The use of other measures should not be ruled out, however, and we encourage further development of evaluative criteria for speech measures designed to probe the effects of DBS or any treatment with potential effects on speech production and communication skills.
KW - Deep brain stimulation
KW - Dysarthria
KW - Intelligibility
KW - Speech physiology
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U2 - 10.1016/j.jneuroling.2011.08.006
DO - 10.1016/j.jneuroling.2011.08.006
M3 - Review article
AN - SCOPUS:84455161030
SN - 0911-6044
VL - 25
SP - 74
EP - 94
JO - Journal of Neurolinguistics
JF - Journal of Neurolinguistics
IS - 2
ER -