Eight non-PKU offspring of phenylketonuric mothers are described. All of the patients have mental subnormality and I.Q./D.Q. scores below those of their mothers. Phenylalanine loading tests failed to discriminate between the nonheterozygotes and the heterozygotes. Growth data from these cases and additional previously unpublished growth data on 13 non-PKU offspring of 3 phenylketonuric mothers demonstrated uniform intrauterine and postnatal growth retardation.
ASJC Scopus subject areas
- Pediatrics, Perinatology, and Child Health