Materials for pharmaceutical dosage forms: Molecular pharmaceutics and controlled release drug delivery aspects

Heidi M. Mansour; Min Ji Sohn; Abeer Al-Ghananeem; Patrick P. DeLuca

doi:10.3390/ijms11093298

Materials for pharmaceutical dosage forms: Molecular pharmaceutics and controlled release drug delivery aspects

Heidi M. Mansour, Min Ji Sohn, Abeer Al-Ghananeem, Patrick P. DeLuca

Research output: Contribution to journal › Review article › peer-review

195 Scopus citations

Abstract

Controlled release delivery is available for many routes of administration and offers many advantages (as microparticles and nanoparticles) over immediate release delivery. These advantages include reduced dosing frequency, better therapeutic control, fewer side effects, and, consequently, these dosage forms are well accepted by patients. Advances in polymer material science, particle engineering design, manufacture, and nanotechnology have led the way to the introduction of several marketed controlled release products and several more are in pre-clinical and clinical development.

Original language	English (US)
Pages (from-to)	3298-3322
Number of pages	25
Journal	International journal of molecular sciences
Volume	11
Issue number	9
DOIs	https://doi.org/10.3390/ijms11093298
State	Published - Sep 2010
Externally published	Yes

Keywords

Biodegradable
Biomaterials
Copolymers
Manufacture
Microparticle
Nanoparticle
Particle engineering design
Pharmaceutical dosage forms
Polymers

ASJC Scopus subject areas

Catalysis
Molecular Biology
Spectroscopy
Computer Science Applications
Physical and Theoretical Chemistry
Organic Chemistry
Inorganic Chemistry

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10.3390/ijms11093298

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abstract = "Controlled release delivery is available for many routes of administration and offers many advantages (as microparticles and nanoparticles) over immediate release delivery. These advantages include reduced dosing frequency, better therapeutic control, fewer side effects, and, consequently, these dosage forms are well accepted by patients. Advances in polymer material science, particle engineering design, manufacture, and nanotechnology have led the way to the introduction of several marketed controlled release products and several more are in pre-clinical and clinical development.",

keywords = "Biodegradable, Biomaterials, Copolymers, Manufacture, Microparticle, Nanoparticle, Particle engineering design, Pharmaceutical dosage forms, Polymers",

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AU - Al-Ghananeem, Abeer

AU - DeLuca, Patrick P.

PY - 2010/9

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AB - Controlled release delivery is available for many routes of administration and offers many advantages (as microparticles and nanoparticles) over immediate release delivery. These advantages include reduced dosing frequency, better therapeutic control, fewer side effects, and, consequently, these dosage forms are well accepted by patients. Advances in polymer material science, particle engineering design, manufacture, and nanotechnology have led the way to the introduction of several marketed controlled release products and several more are in pre-clinical and clinical development.

KW - Biodegradable

KW - Biomaterials

KW - Copolymers

KW - Manufacture

KW - Microparticle

KW - Nanoparticle

KW - Particle engineering design

KW - Pharmaceutical dosage forms

KW - Polymers

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Materials for pharmaceutical dosage forms: Molecular pharmaceutics and controlled release drug delivery aspects

Abstract

Keywords

ASJC Scopus subject areas

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