Mast cell cholangiopathy: Another cause of sclerosing cholangitis

Todd H. Baron, Robert E. Koehler, William H. Rodgers, Michael B. Fallon, Susan M. Ferguson

Research output: Contribution to journalArticlepeer-review

47 Scopus citations


A 75-year-old woman with known systemic mastocytosis presented with abdominal pain, ascites, and bile duct thickening on computed tomography and ultrasonography. A liver biopsy specimen showed infiltration with mast cells. Endoscopic retrograde cholangiography showed ductal changes compatible with those found in primary sclerosing cholangitis. Brush cytology of the intrahepatic bile ducts confirmed mast cell infiltration. Systemic mastocytosis can infiltrate the biliary system, producing a cholangiopathy radiographically similar to primary sclerosing cholangitis.

Original languageEnglish (US)
Pages (from-to)1677-1681
Number of pages5
Issue number5
StatePublished - Nov 1995

ASJC Scopus subject areas

  • Hepatology
  • Gastroenterology


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