Mammographic imaging with a small format CCD-based digital cassette: Physical characteristics of a clinical system

Srinivasan Vedantham, Andrew Karellas, Sankararaman Suryanarayanan, Ilias Levis, Michel Sayag, Robert Kleehammer, Robert Heidsieck, Carl J. D'Orsi

Research output: Contribution to journalArticlepeer-review

58 Scopus citations


The physical characteristics of a clinical charge coupled device (CCD)-based imager (Senovision, GE Medical Systems, Milwaukee, WI) for small-field digital mammography have been investigated. The imager employs a MinR 2000(TM) (Eastman Kodak Company, Rochester, NY) scintillator coupled by a 1:1 optical fiber to a front-illuminated 61 X 61 mm CCD operating at a pixel pitch of 30 microns. Objective criteria such as modulation transfer function (MTF), noise power spectrum (NPS), detective quantum efficiency (DQE), and noise equivalent quanta (NEQ) were employed for this evaluation. The results demonstrated a limiting spatial resolution (10% MTF) of 10 cy/mm. The measured DQE of the current prototype utilizing a 28 kVp, Mo-Mo spectrum beam hardened with 4.5 cm Lucite is ~40% at close to zero spatial frequency at an exposure of 8.2 mR, and decreases to ~28% at a low exposure of 1.1 mR. Detector element nonuniformity and electronic gain variations were not significant after appropriate calibration and software corrections. The response of the imager was linear and did not exhibit signal saturation under tested exposure conditions. (C) 2000 American Association of Physicists in Medicine.

Original languageEnglish (US)
Pages (from-to)1832-1840
Number of pages9
JournalMedical physics
Issue number8
StatePublished - Aug 2000


  • Breast imaging
  • Detective quantum efficiency (DQE)
  • Digital mammography
  • Image quality
  • Physics

ASJC Scopus subject areas

  • Biophysics
  • Radiology Nuclear Medicine and imaging


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