TY - JOUR
T1 - Macrophages and resistance to JHM virus CNS infection.
AU - Stohlman, S. A.
AU - Frelinger, J. A.
PY - 1981
Y1 - 1981
N2 - Thioglycollate elicited peritoneal exudate cells from resistant SJL mice, younger susceptible SJL mice, and susceptible ASW, BALB/c, and C57/BL6 mice all exhibit extrinsic antiviral activity. The active cell was characterized as a Thy 1.2 negative, Ia negative, radiation resistant adherent cell. The antiviral activity was not due to nonspecific cellular cytotoxicity directed against the susceptible cell nor interferon. Adherent PE cells from resistant and susceptible SJL mice were similar with respect to the number of phagocytes, nonspecific esterase containing, Fc, and C3b receptor bearing cells. Finally, extrinsic antiviral activity was not dependent upon intrinsic antiviral activity.
AB - Thioglycollate elicited peritoneal exudate cells from resistant SJL mice, younger susceptible SJL mice, and susceptible ASW, BALB/c, and C57/BL6 mice all exhibit extrinsic antiviral activity. The active cell was characterized as a Thy 1.2 negative, Ia negative, radiation resistant adherent cell. The antiviral activity was not due to nonspecific cellular cytotoxicity directed against the susceptible cell nor interferon. Adherent PE cells from resistant and susceptible SJL mice were similar with respect to the number of phagocytes, nonspecific esterase containing, Fc, and C3b receptor bearing cells. Finally, extrinsic antiviral activity was not dependent upon intrinsic antiviral activity.
UR - http://www.scopus.com/inward/record.url?scp=0019743461&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0019743461&partnerID=8YFLogxK
U2 - 10.1007/978-1-4757-0456-3_32
DO - 10.1007/978-1-4757-0456-3_32
M3 - Article
C2 - 6278893
AN - SCOPUS:0019743461
VL - 142
SP - 387
EP - 398
JO - Advances in Experimental Medicine and Biology
JF - Advances in Experimental Medicine and Biology
SN - 0065-2598
ER -