Abstract
Although described since ancient times, the lymphatic system was not fully recognized as an integrated vasculature, circulation, and center of the immune network until the discipline of lymphology was established a little more than half a century ago. This chapter reviews its distinctive macroscopic and microscopic anatomy and the physiologic principles governing lymph formation, absorption, and propulsion. In addition, we discuss the pathobiology and therapeutic implications underlying common lymphatic disorders. Finally, links to cancer, its complications, and spread are highlighted.
Original language | English (US) |
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Title of host publication | Cancer Metastasis Through the Lymphovascular System |
Publisher | Springer International Publishing |
Pages | 187-198 |
Number of pages | 12 |
ISBN (Electronic) | 9783030930844 |
ISBN (Print) | 9783030930837 |
DOIs | |
State | Published - Jan 1 2022 |
Keywords
- Cancer
- Lymphatic anatomy
- Lymphatic pathophysiology
- Lymphatic physiology
- Lymphatic systemomics
- Lymphogenous metastasis
- Molecular lymphology
ASJC Scopus subject areas
- General Medicine
- General Immunology and Microbiology