Lymphangioleiomyomatosis and SZ α1-antitrypsin disease: A unique combination?

Andrew L. Chan; Sunye Kwack; Kirk D. Jones; Marilyn K. Glassberg; Charles R. Gherman

doi:10.1378/chest.124.2.763

Lymphangioleiomyomatosis and SZ α₁-antitrypsin disease: A unique combination?

Andrew L. Chan, Sunye Kwack, Kirk D. Jones, Marilyn K. Glassberg, Charles R. Gherman

Research output: Contribution to journal › Article › peer-review

6 Scopus citations

Abstract

We deseribe a case of a 37-year-old female ex-smoker with lymphangioleiomyomatosis and SZ α₁-antitrypsin disease who underwent successful bilateral sequential lung transplantation. While this disease combination has not been described previously, we recommend vigilance for the possibility of sueh combinations in patients with chronic lung disease. The possible mechanisms of interaction resulting from both disease processes are discussed.

Original language	English (US)
Pages (from-to)	763-765
Number of pages	3
Journal	CHEST
Volume	124
Issue number	2
DOIs	https://doi.org/10.1378/chest.124.2.763
State	Published - Aug 1 2003
Externally published	Yes

Keywords

COPD
Chylothorax
Lymphangioleiomyomatosis
Matrix metalloproteinase
SZ α-antitrypsin disease

ASJC Scopus subject areas

Pulmonary and Respiratory Medicine
Critical Care and Intensive Care Medicine
Cardiology and Cardiovascular Medicine

Access to Document

10.1378/chest.124.2.763

Cite this

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title = "Lymphangioleiomyomatosis and SZ α1-antitrypsin disease: A unique combination?",

abstract = "We deseribe a case of a 37-year-old female ex-smoker with lymphangioleiomyomatosis and SZ α1-antitrypsin disease who underwent successful bilateral sequential lung transplantation. While this disease combination has not been described previously, we recommend vigilance for the possibility of sueh combinations in patients with chronic lung disease. The possible mechanisms of interaction resulting from both disease processes are discussed.",

keywords = "COPD, Chylothorax, Lymphangioleiomyomatosis, Matrix metalloproteinase, SZ α-antitrypsin disease",

author = "Chan, {Andrew L.} and Sunye Kwack and Jones, {Kirk D.} and Glassberg, {Marilyn K.} and Gherman, {Charles R.}",

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AU - Kwack, Sunye

AU - Jones, Kirk D.

AU - Glassberg, Marilyn K.

AU - Gherman, Charles R.

PY - 2003/8/1

Y1 - 2003/8/1

N2 - We deseribe a case of a 37-year-old female ex-smoker with lymphangioleiomyomatosis and SZ α1-antitrypsin disease who underwent successful bilateral sequential lung transplantation. While this disease combination has not been described previously, we recommend vigilance for the possibility of sueh combinations in patients with chronic lung disease. The possible mechanisms of interaction resulting from both disease processes are discussed.

AB - We deseribe a case of a 37-year-old female ex-smoker with lymphangioleiomyomatosis and SZ α1-antitrypsin disease who underwent successful bilateral sequential lung transplantation. While this disease combination has not been described previously, we recommend vigilance for the possibility of sueh combinations in patients with chronic lung disease. The possible mechanisms of interaction resulting from both disease processes are discussed.

KW - COPD

KW - Chylothorax

KW - Lymphangioleiomyomatosis

KW - Matrix metalloproteinase

KW - SZ α-antitrypsin disease

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