TY - JOUR
T1 - Lower respiratory illnesses in childhood are associated with the presence of air trapping in early adulthood
AU - Polverino, Francesca
AU - Stern, Debra A.
AU - Snyder, Eric M.
AU - Wheatley-Guy, Courtney
AU - Bhatt, Surya P.
AU - Martinez, Fernando D.
AU - Guerra, Stefano
AU - Morgan, Wayne J.
N1 - Publisher Copyright:
© 2022 The Author(s)
PY - 2023/1
Y1 - 2023/1
N2 - Several factors occurring in early life, including lower respiratory tract illnesses (LRIs), are involved in determining lung structure and function in adulthood, but the effects of these factors on lung development remain largely unknown. Hereby, we evaluated the parameters from computed tomography (CT) scans performed at the age of 26 years in 39 subjects from the birth cohort of the Tucson Children's Respiratory Study (TCRS) in order to determine the relationship between early childhood factors and lung structural changes in young adult life. We found that participants with LRIs in childhood had increased air trapping at the age of 26 suggesting an association between childhood infections and lung development.
AB - Several factors occurring in early life, including lower respiratory tract illnesses (LRIs), are involved in determining lung structure and function in adulthood, but the effects of these factors on lung development remain largely unknown. Hereby, we evaluated the parameters from computed tomography (CT) scans performed at the age of 26 years in 39 subjects from the birth cohort of the Tucson Children's Respiratory Study (TCRS) in order to determine the relationship between early childhood factors and lung structural changes in young adult life. We found that participants with LRIs in childhood had increased air trapping at the age of 26 suggesting an association between childhood infections and lung development.
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U2 - 10.1016/j.rmed.2022.107062
DO - 10.1016/j.rmed.2022.107062
M3 - Article
C2 - 36508986
AN - SCOPUS:85143989208
SN - 0954-6111
VL - 206
JO - Respiratory Medicine
JF - Respiratory Medicine
M1 - 107062
ER -