Lower respiratory illnesses in childhood are associated with the presence of air trapping in early adulthood

Francesca Polverino, Debra A. Stern, Eric M. Snyder, Courtney Wheatley-Guy, Surya P. Bhatt, Fernando D. Martinez, Stefano Guerra, Wayne J. Morgan

Research output: Contribution to journalArticlepeer-review

3 Scopus citations

Abstract

Several factors occurring in early life, including lower respiratory tract illnesses (LRIs), are involved in determining lung structure and function in adulthood, but the effects of these factors on lung development remain largely unknown. Hereby, we evaluated the parameters from computed tomography (CT) scans performed at the age of 26 years in 39 subjects from the birth cohort of the Tucson Children's Respiratory Study (TCRS) in order to determine the relationship between early childhood factors and lung structural changes in young adult life. We found that participants with LRIs in childhood had increased air trapping at the age of 26 suggesting an association between childhood infections and lung development.

Original languageEnglish (US)
Article number107062
JournalRespiratory Medicine
Volume206
DOIs
StatePublished - Jan 2023

ASJC Scopus subject areas

  • Pulmonary and Respiratory Medicine

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